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Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice.
Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K. Morgan DJ, et al. Among authors: mackie k. J Neurosci. 2014 Apr 9;34(15):5152-63. doi: 10.1523/JNEUROSCI.3445-12.2014. J Neurosci. 2014. PMID: 24719095 Free PMC article.
Long-term consequences of perinatal fatty acid amino hydrolase inhibition.
Wu CS, Morgan D, Jew CP, Haskins C, Andrews MJ, Leishman E, Spencer CM, Czyzyk T, Bradshaw H, Mackie K, Lu HC. Wu CS, et al. Among authors: mackie k. Br J Pharmacol. 2014 Mar;171(6):1420-34. doi: 10.1111/bph.12500. Br J Pharmacol. 2014. PMID: 24730060 Free PMC article.
Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation.
Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE. Smith TH, et al. Among authors: mackie k. Mol Pharmacol. 2015 Apr;87(4):747-65. doi: 10.1124/mol.114.096495. Epub 2015 Feb 5. Mol Pharmacol. 2015. PMID: 25657338 Free PMC article.
Endocannabinoid signalling modulates susceptibility to traumatic stress exposure.
Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, Patel S. Bluett RJ, et al. Among authors: mackie k. Nat Commun. 2017 Mar 28;8:14782. doi: 10.1038/ncomms14782. Nat Commun. 2017. PMID: 28348378 Free PMC article.
479 results