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Methotrexate treatment hampers induction of vaccine-specific CD4 T cell responses in patients with IMID.
Kummer LYL, Fernández Blanco L, Kreher C, Bos A, Kuijper LH, Verstegen NJM, van de Sandt CE, Konijn VAL, Duurland MC, Menage C, Jorritsma T, Steenhuis M, Hagen RR, van den Dijssel J, de Jongh R, Ashhurst T, van Gils MJ, Garcia-Vallejo JJ, Claireaux M, Stalman EW, van Dam KPJ, Wieske L, Boekel L, Wolbink G, Tas SW, Rispens T, Kuijpers TW, Eftimov F, van Ham SM, Ten Brinke A; T2B! Immunity Against SARS-CoV-2 Study Group. Kummer LYL, et al. Among authors: tas sw. RMD Open. 2024 Oct 7;10(4):e004664. doi: 10.1136/rmdopen-2024-004664. RMD Open. 2024. PMID: 39375177 Free PMC article.
A deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion.
Ochoa S, Hsu AP, Oler AJ, Kumar D, Chauss D, van Hamburg JP, van Laar GG, Oikonomou V, Ganesan S, Ferré EMN, Schmitt MM, DiMaggio T, Barber P, Constantine GM, Rosen LB, Auwaerter PG, Gandhi B, Miller JL, Eisenberg R, Rubinstein A, Schussler E, Balliu E, Shashi V, Neth O, Olbrich P, Le KM, Mamia N, Laakso S, Nevalainen PI, Grönholm J, Seppänen MRJ, Boon L, Uzel G, Franco LM, Heller T, Winer KK, Ghosh R, Seifert BA, Walkiewicz M, Notarangelo LD, Zhou Q, Askentijevich I, Gahl W, Dalgard CL, Perera L, Afzali B, Tas SW, Holland SM, Lionakis MS. Ochoa S, et al. Among authors: tas sw. Sci Transl Med. 2024 Sep 18;16(765):eadk0845. doi: 10.1126/scitranslmed.adk0845. Epub 2024 Sep 18. Sci Transl Med. 2024. PMID: 39292801
388 results