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Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.
Nakagawa H, Suzuki N, Hirata Y, Hikiba Y, Hayakawa Y, Kinoshita H, Ihara S, Uchino K, Nishikawa Y, Ijichi H, Otsuka M, Arita J, Sakamoto Y, Hasegawa K, Kokudo N, Tateishi K, Koike K. Nakagawa H, et al. Among authors: koike k. Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3806-E3815. doi: 10.1073/pnas.1619416114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28439013 Free PMC article.
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S. Nakagawa H, et al. Among authors: koike k. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1090-5. doi: 10.1073/pnas.1322731111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395807 Free PMC article.
Peribiliary Glands as the Cellular Origin of Biliary Tract Cancer.
Nakagawa H, Hayata Y, Yamada T, Kawamura S, Suzuki N, Koike K. Nakagawa H, et al. Among authors: koike k. Int J Mol Sci. 2018 Jun 12;19(6):1745. doi: 10.3390/ijms19061745. Int J Mol Sci. 2018. PMID: 29895797 Free PMC article. Review.
Axin2+ Peribiliary Glands in the Periampullary Region Generate Biliary Epithelial Stem Cells That Give Rise to Ampullary Carcinoma.
Hayata Y, Nakagawa H, Kurosaki S, Kawamura S, Matsushita Y, Hayakawa Y, Suzuki N, Hata M, Tsuboi M, Kinoshita H, Miyabayashi K, Mizutani H, Nakagomi R, Ikenoue T, Hirata Y, Arita J, Hasegawa K, Tateishi K, Koike K. Hayata Y, et al. Among authors: koike k. Gastroenterology. 2021 May;160(6):2133-2148.e6. doi: 10.1053/j.gastro.2021.01.028. Epub 2021 Jan 16. Gastroenterology. 2021. PMID: 33465373 Free article.
Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Kinoshita H, Nakata W, Takahashi R, Tateishi K, Tada M, Akanuma M, Yoshida H, Takeda K, Ichijo H, Omata M, Maeda S, Koike K. Hayakawa Y, et al. Among authors: koike k. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):780-5. doi: 10.1073/pnas.1011418108. Epub 2010 Dec 27. Proc Natl Acad Sci U S A. 2011. PMID: 21187402 Free PMC article.
Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.
Takahashi R, Hirata Y, Sakitani K, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Sakamoto K, Hikiba Y, Ijichi H, Moses HL, Maeda S, Koike K. Takahashi R, et al. Among authors: koike k. Cancer Sci. 2013 Mar;104(3):337-44. doi: 10.1111/cas.12080. Epub 2013 Jan 24. Cancer Sci. 2013. PMID: 23237571 Free PMC article.
Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis.
Kinoshita H, Hirata Y, Nakagawa H, Sakamoto K, Hayakawa Y, Takahashi R, Nakata W, Sakitani K, Serizawa T, Hikiba Y, Akanuma M, Shibata W, Maeda S, Koike K. Kinoshita H, et al. Among authors: koike k. PLoS One. 2013 Apr 12;8(4):e60914. doi: 10.1371/journal.pone.0060914. Print 2013. PLoS One. 2013. PMID: 23593346 Free PMC article.
Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.
Yamamoto K, Tateishi K, Kudo Y, Sato T, Yamamoto S, Miyabayashi K, Matsusaka K, Asaoka Y, Ijichi H, Hirata Y, Otsuka M, Nakai Y, Isayama H, Ikenoue T, Kurokawa M, Fukayama M, Kokudo N, Omata M, Koike K. Yamamoto K, et al. Among authors: koike k. Carcinogenesis. 2014 Nov;35(11):2404-14. doi: 10.1093/carcin/bgu136. Epub 2014 Jun 19. Carcinogenesis. 2014. PMID: 24947179
Characterization of a new small bowel adenocarcinoma cell line and screening of anti-cancer drug against small bowel adenocarcinoma.
Suzuki H, Hirata Y, Suzuki N, Ihara S, Sakitani K, Kobayashi Y, Kinoshita H, Hayakawa Y, Yamada A, Watabe H, Tateishi K, Ikenoue T, Yamaji Y, Koike K. Suzuki H, et al. Among authors: koike k. Am J Pathol. 2015 Feb;185(2):550-62. doi: 10.1016/j.ajpath.2014.10.006. Epub 2014 Dec 2. Am J Pathol. 2015. PMID: 25478808 Free article.
3,120 results