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Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms.
Jaramillo CAC, Belli S, Cascais AC, Dudal S, Edelmann MR, Haak M, Brun ME, Otteneder MB, Ullah M, Funk C, Schuler F, Simon S. Jaramillo CAC, et al. Among authors: otteneder mb. MAbs. 2017 Jul;9(5):781-791. doi: 10.1080/19420862.2017.1320008. Epub 2017 Apr 25. MAbs. 2017. PMID: 28440708 Free PMC article.
Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.
Zheng Y, Tesar DB, Benincosa L, Birnböck H, Boswell CA, Bumbaca D, Cowan KJ, Danilenko DM, Daugherty AL, Fielder PJ, Grimm HP, Joshi A, Justies N, Kolaitis G, Lewin-Koh N, Li J, McVay S, O'Mahony J, Otteneder M, Pantze M, Putnam WS, Qiu ZJ, Ruppel J, Singer T, Stauch O, Theil FP, Visich J, Yang J, Ying Y, Khawli LA, Richter WF. Zheng Y, et al. MAbs. 2012 Mar-Apr;4(2):243-55. doi: 10.4161/mabs.4.2.19387. Epub 2012 Mar 1. MAbs. 2012. PMID: 22453096 Free PMC article.
Distribution of FcRn Across Species and Tissues.
Latvala S, Jacobsen B, Otteneder MB, Herrmann A, Kronenberg S. Latvala S, et al. Among authors: otteneder mb. J Histochem Cytochem. 2017 Jun;65(6):321-333. doi: 10.1369/0022155417705095. Epub 2017 Apr 12. J Histochem Cytochem. 2017. PMID: 28402755 Free PMC article.
Quantification of IgG monoclonal antibody clearance in tissues.
Eigenmann MJ, Fronton L, Grimm HP, Otteneder MB, Krippendorff BF. Eigenmann MJ, et al. Among authors: otteneder mb. MAbs. 2017 Aug/Sep;9(6):1007-1015. doi: 10.1080/19420862.2017.1337619. Epub 2017 Jun 14. MAbs. 2017. PMID: 28613103 Free PMC article.
25 results