Yokota T - Search Results

1

Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients With Cancer.

Katakami N, Oda K, Tauchi K, Nakata K, Shinozaki K, Yokota T, Suzuki Y, Narabayashi M, Boku N. Katakami N, et al. Among authors: yokota t. J Clin Oncol. 2017 Jun 10;35(17):1921-1928. doi: 10.1200/JCO.2016.70.8453. Epub 2017 Apr 26. J Clin Oncol. 2017. PMID: 28445097 Clinical Trial.

2

Phase 1, Randomized, Double-Blind, Placebo-Controlled Studies on the Safety, Tolerability, and Pharmacokinetics of Naldemedine in Healthy Volunteers.

Fukumura K, Yokota T, Baba Y, Arjona Ferreira JC. Fukumura K, et al. Among authors: yokota t. Clin Pharmacol Drug Dev. 2018 Jun;7(5):474-483. doi: 10.1002/cpdd.387. Epub 2017 Sep 27. Clin Pharmacol Drug Dev. 2018. PMID: 28960888 Clinical Trial.

3

Randomized Phase III and Extension Studies of Naldemedine in Patients With Opioid-Induced Constipation and Cancer.

Katakami N, Harada T, Murata T, Shinozaki K, Tsutsumi M, Yokota T, Arai M, Tada Y, Narabayashi M, Boku N. Katakami N, et al. Among authors: yokota t. J Clin Oncol. 2017 Dec 1;35(34):3859-3866. doi: 10.1200/JCO.2017.73.0853. Epub 2017 Oct 2. J Clin Oncol. 2017. PMID: 28968171 Clinical Trial.

4

Reply to Y. Yagi et al.

Katakami N, Yokota T, Tada Y. Katakami N, et al. Among authors: yokota t. J Clin Oncol. 2018 Apr 1;36(10):1050. doi: 10.1200/JCO.2017.77.0925. Epub 2018 Feb 6. J Clin Oncol. 2018. PMID: 29406802 No abstract available.

5

Naldemedine in Japanese patients with opioid-induced constipation and chronic noncancer pain: open-label Phase III studies.

Saito Y, Yokota T, Arai M, Tada Y, Sumitani M. Saito Y, et al. Among authors: yokota t. J Pain Res. 2018 Dec 24;12:127-138. doi: 10.2147/JPR.S175900. eCollection 2019. J Pain Res. 2018. PMID: 30613161 Free PMC article.

6

The Influence of Renal or Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Naldemedine.

Fukumura K, Yamada T, Yokota T, Kawasaki A. Fukumura K, et al. Among authors: yokota t. Clin Pharmacol Drug Dev. 2020 Feb;9(2):162-174. doi: 10.1002/cpdd.690. Epub 2019 Apr 12. Clin Pharmacol Drug Dev. 2020. PMID: 30977959 Free PMC article. Clinical Trial.

7

Safety and efficacy of naldemedine in cancer patients with opioid-induced constipation: a pooled, subgroup analysis of two randomised controlled studies.

Osaka I, Ishiki H, Yokota T, Tada Y, Sato H, Okamoto M, Satomi E. Osaka I, et al. Among authors: yokota t. ESMO Open. 2019 Jul 31;4(4):e000527. doi: 10.1136/esmoopen-2019-000527. eCollection 2019. ESMO Open. 2019. PMID: 31423335 Free PMC article.

8

Naldemedine: Peripherally Acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects.

Inagaki M, Kanemasa T, Yokota T. Inagaki M, et al. Among authors: yokota t. Curr Top Med Chem. 2020;20(31):2830-2842. doi: 10.2174/1568026620666200710105953. Curr Top Med Chem. 2020. PMID: 32648846 Review.

9

Effect of add-on naldemedine treatment in patients with cancer and opioid-induced constipation insufficiently responding to magnesium oxide: a pooled, subgroup analysis of two randomized controlled trials.

Kessoku T, Akamatsu T, Morioka Y, Yokota T, Kobayashi M, Uchida K, Koretaka Y, Nakajima A. Kessoku T, et al. Among authors: yokota t. Jpn J Clin Oncol. 2024 Oct 1:hyae135. doi: 10.1093/jjco/hyae135. Online ahead of print. Jpn J Clin Oncol. 2024. PMID: 39354673

10

Naldemedine is effective in the treatment of opioid-induced constipation in patients with chronic non-cancer pain who had a poor response to laxatives.

Hale ME, Wild JE, Yamada T, Yokota T, Tack J, Andresen V, Drewes AM. Hale ME, et al. Among authors: yokota t. Therap Adv Gastroenterol. 2021 Jul 31;14:17562848211032320. doi: 10.1177/17562848211032320. eCollection 2021. Therap Adv Gastroenterol. 2021. PMID: 34377150 Free PMC article.

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