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PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.
Day TA, Layer JV, Cleary JP, Guha S, Stevenson KE, Tivey T, Kim S, Schinzel AC, Izzo F, Doench J, Root DE, Hahn WC, Price BD, Weinstock DM. Day TA, et al. Among authors: schinzel ac. Nat Commun. 2017 Apr 27;8:15110. doi: 10.1038/ncomms15110. Nat Commun. 2017. PMID: 28447610 Free PMC article.
Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.
Day TA, Layer JV, Cleary JP, Guha S, Stevenson KE, Tivey T, Kim S, Schinzel AC, Izzo F, Doench J, Root DE, Hahn WC, Price BD, Weinstock DM. Day TA, et al. Among authors: schinzel ac. Nat Commun. 2017 Jun 13;8:15918. doi: 10.1038/ncomms15918. Nat Commun. 2017. PMID: 28607496 Free PMC article.
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. Barbie DA, et al. Among authors: schinzel ac. Nature. 2009 Nov 5;462(7269):108-12. doi: 10.1038/nature08460. Epub 2009 Oct 21. Nature. 2009. PMID: 19847166 Free PMC article.
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, Taylor JE, Stegmaier K, Jaffe JD, Bustin M, te Kronnie G, Izraeli S, Harris MH, Stevenson KE, Neuberg D, Silverman LB, Sallan SE, Bradner JE, Hahn WC, Crispino JD, Pellman D, Weinstock DM. Lane AA, et al. Among authors: schinzel ac. Nat Genet. 2014 Jun;46(6):618-23. doi: 10.1038/ng.2949. Epub 2014 Apr 20. Nat Genet. 2014. PMID: 24747640 Free PMC article.
CK1epsilon is required for breast cancers dependent on beta-catenin activity.
Kim SY, Dunn IF, Firestein R, Gupta P, Wardwell L, Repich K, Schinzel AC, Wittner B, Silver SJ, Root DE, Boehm JS, Ramaswamy S, Lander ES, Hahn WC. Kim SY, et al. Among authors: schinzel ac. PLoS One. 2010 Feb 1;5(2):e8979. doi: 10.1371/journal.pone.0008979. PLoS One. 2010. PMID: 20126544 Free PMC article.
Integrative genomic approaches to understanding cancer.
Hahn WC, Dunn IF, Kim SY, Schinzel AC, Firestein R, Guney I, Boehm JS. Hahn WC, et al. Among authors: schinzel ac. Biochim Biophys Acta. 2009 Jun;1790(6):478-84. doi: 10.1016/j.bbagen.2009.02.003. Epub 2009 Feb 11. Biochim Biophys Acta. 2009. PMID: 19364473 Free PMC article. Review.
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC. Rosenbluh J, et al. Among authors: schinzel ac. Cell. 2012 Dec 21;151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Cell. 2012. PMID: 23245941 Free PMC article.
34 results