Ortega J - Search Results

1

The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans.

Manhart CM, Ni X, White MA, Ortega J, Surtees JA, Alani E. Manhart CM, et al. Among authors: ortega j. PLoS Biol. 2017 Apr 28;15(4):e2001164. doi: 10.1371/journal.pbio.2001164. eCollection 2017 Apr. PLoS Biol. 2017. PMID: 28453523 Free PMC article.

2

Molecular Mechanism for the (-)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers.

Ahmed R, VanSchouwen B, Jafari N, Ni X, Ortega J, Melacini G. Ahmed R, et al. Among authors: ortega j. J Am Chem Soc. 2017 Oct 4;139(39):13720-13734. doi: 10.1021/jacs.7b05012. Epub 2017 Aug 25. J Am Chem Soc. 2017. PMID: 28841302

3

Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.

Seffouh A, Jain N, Jahagirdar D, Basu K, Razi A, Ni X, Guarné A, Britton RA, Ortega J. Seffouh A, et al. Among authors: ortega j. Nucleic Acids Res. 2019 Nov 4;47(19):10414-10425. doi: 10.1093/nar/gkz770. Nucleic Acids Res. 2019. PMID: 31665744 Free PMC article.

4

YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit.

Ni X, Davis JH, Jain N, Razi A, Benlekbir S, McArthur AG, Rubinstein JL, Britton RA, Williamson JR, Ortega J. Ni X, et al. Among authors: ortega j. Nucleic Acids Res. 2016 Sep 30;44(17):8442-55. doi: 10.1093/nar/gkw678. Epub 2016 Aug 2. Nucleic Acids Res. 2016. PMID: 27484475 Free PMC article.

5

Yeast rvb1 and rvb2 proteins oligomerize as a conformationally variable dodecamer with low frequency.

Jeganathan A, Leong V, Zhao L, Huen J, Nano N, Houry WA, Ortega J. Jeganathan A, et al. Among authors: ortega j. J Mol Biol. 2015 May 22;427(10):1875-86. doi: 10.1016/j.jmb.2015.01.010. Epub 2015 Jan 28. J Mol Biol. 2015. PMID: 25636407

6

Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.

Li DH, Chung YS, Gloyd M, Joseph E, Ghirlando R, Wright GD, Cheng YQ, Maurizi MR, Guarné A, Ortega J. Li DH, et al. Among authors: ortega j. Chem Biol. 2010 Sep 24;17(9):959-69. doi: 10.1016/j.chembiol.2010.07.008. Chem Biol. 2010. PMID: 20851345 Free PMC article.

7

ClpP: a structurally dynamic protease regulated by AAA+ proteins.

Alexopoulos JA, Guarné A, Ortega J. Alexopoulos JA, et al. Among authors: ortega j. J Struct Biol. 2012 Aug;179(2):202-10. doi: 10.1016/j.jsb.2012.05.003. Epub 2012 May 14. J Struct Biol. 2012. PMID: 22595189 Review.

8

Structural determinants stabilizing the axial channel of ClpP for substrate translocation.

Alexopoulos J, Ahsan B, Homchaudhuri L, Husain N, Cheng YQ, Ortega J. Alexopoulos J, et al. Among authors: ortega j. Mol Microbiol. 2013 Oct;90(1):167-80. doi: 10.1111/mmi.12356. Epub 2013 Aug 23. Mol Microbiol. 2013. PMID: 23927726 Free article.

9

The impact of recent improvements in cryo-electron microscopy technology on the understanding of bacterial ribosome assembly.

Razi A, Britton RA, Ortega J. Razi A, et al. Among authors: ortega j. Nucleic Acids Res. 2017 Feb 17;45(3):1027-1040. doi: 10.1093/nar/gkw1231. Nucleic Acids Res. 2017. PMID: 28180306 Free PMC article. Review.

10

Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states.

Algamal M, Ahmed R, Jafari N, Ahsan B, Ortega J, Melacini G. Algamal M, et al. Among authors: ortega j. J Biol Chem. 2017 Oct 20;292(42):17158-17168. doi: 10.1074/jbc.M117.792853. Epub 2017 Aug 10. J Biol Chem. 2017. PMID: 28798235 Free PMC article.

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