Srinivasan T - Search Results

1

A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.

Chen KY, Srinivasan T, Tung KL, Belmonte JM, Wang L, Murthy PKL, Choi J, Rakhilin N, King S, Varanko AK, Witherspoon M, Nishimura N, Glazier JA, Lipkin SM, Bu P, Shen X. Chen KY, et al. Among authors: srinivasan t. Mol Syst Biol. 2017 Apr 28;13(4):927. doi: 10.15252/msb.20167324. Mol Syst Biol. 2017. PMID: 28455349 Free PMC article.

2

Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.

Srinivasan T, Than EB, Bu P, Tung KL, Chen KY, Augenlicht L, Lipkin SM, Shen X. Srinivasan T, et al. Sci Rep. 2016 May 16;6:26069. doi: 10.1038/srep26069. Sci Rep. 2016. PMID: 27181744 Free PMC article.

3

Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis.

Kadur Lakshminarasimha Murthy P, Srinivasan T, Bochter MS, Xi R, Varanko AK, Tung KL, Semerci F, Xu K, Maletic-Savatic M, Cole SE, Shen X. Kadur Lakshminarasimha Murthy P, et al. Among authors: srinivasan t. Elife. 2018 Apr 9;7:e35710. doi: 10.7554/eLife.35710. Elife. 2018. PMID: 29629872 Free PMC article.

4

A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.

Bu P, Wang L, Chen KY, Srinivasan T, Murthy PK, Tung KL, Varanko AK, Chen HJ, Ai Y, King S, Lipkin SM, Shen X. Bu P, et al. Among authors: srinivasan t. Cell Stem Cell. 2016 Feb 4;18(2):189-202. doi: 10.1016/j.stem.2016.01.006. Cell Stem Cell. 2016. PMID: 26849305 Free PMC article.

5

NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.

Srinivasan T, Walters J, Bu P, Than EB, Tung KL, Chen KY, Panarelli N, Milsom J, Augenlicht L, Lipkin SM, Shen X. Srinivasan T, et al. Cancer Res. 2016 Jun 1;76(11):3411-21. doi: 10.1158/0008-5472.CAN-15-3198. Epub 2016 Apr 11. Cancer Res. 2016. PMID: 27197180 Free PMC article.

6

A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.

Wang L, Bu P, Ai Y, Srinivasan T, Chen HJ, Xiang K, Lipkin SM, Shen X. Wang L, et al. Among authors: srinivasan t. Elife. 2016 Apr 14;5:e14620. doi: 10.7554/eLife.14620. Elife. 2016. PMID: 27077950 Free PMC article.

7

Single-Cell Transcriptomics Reveals Heterogeneity and Drug Response of Human Colorectal Cancer Organoids.

Chen KY, Srinivasan T, Lin C, Tung KL, Gao Z, Hsu DS, Lipkin SM, Shen X. Chen KY, et al. Among authors: srinivasan t. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:2378-2381. doi: 10.1109/EMBC.2018.8512784. Annu Int Conf IEEE Eng Med Biol Soc. 2018. PMID: 30440885 Free PMC article.

8

The Ex Vivo Culture and Pattern Recognition Receptor Stimulation of Mouse Intestinal Organoids.

Rothschild DE, Srinivasan T, Aponte-Santiago LA, Shen X, Allen IC. Rothschild DE, et al. Among authors: srinivasan t. J Vis Exp. 2016 May 18;(111):54033. doi: 10.3791/54033. J Vis Exp. 2016. PMID: 27285214 Free PMC article.

9

Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.

Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S. Crespo M, et al. Among authors: srinivasan t. Nat Med. 2017 Jul;23(7):878-884. doi: 10.1038/nm.4355. Epub 2017 Jun 19. Nat Med. 2017. PMID: 28628110 Free PMC article.

10

Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.

Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S. Crespo M, et al. Among authors: srinivasan t. Nat Med. 2018 Apr 10;24(4):526. doi: 10.1038/nm0418-526a. Nat Med. 2018. PMID: 29634683

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