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Page 1
Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine.
Clendenen N, Nunns GR, Moore EE, Reisz JA, Gonzalez E, Peltz E, Silliman CC, Fragoso M, Nemkov T, Wither MJ, Hansen K, Banerjee A, Moore HB, DʼAlessandro A. Clendenen N, et al. Among authors: wither mj. J Trauma Acute Care Surg. 2017 Oct;83(4):635-642. doi: 10.1097/TA.0000000000001504. J Trauma Acute Care Surg. 2017. PMID: 28463938 Free PMC article.
Plasma First Resuscitation Reduces Lactate Acidosis, Enhances Redox Homeostasis, Amino Acid and Purine Catabolism in a Rat Model of Profound Hemorrhagic Shock.
D'Alessandro A, Moore HB, Moore EE, Wither MJ, Nemkov T, Morton AP, Gonzalez E, Chapman MP, Fragoso M, Slaughter A, Sauaia A, Silliman CC, Hansen KC, Banerjee A. D'Alessandro A, et al. Among authors: wither mj. Shock. 2016 Aug;46(2):173-82. doi: 10.1097/SHK.0000000000000588. Shock. 2016. PMID: 26863033 Free PMC article.
Plasma succinate is a predictor of mortality in critically injured patients.
DʼAlessandro A, Moore HB, Moore EE, Reisz JA, Wither MJ, Ghasasbyan A, Chandler J, Silliman CC, Hansen KC, Banerjee A. DʼAlessandro A, et al. Among authors: wither mj. J Trauma Acute Care Surg. 2017 Sep;83(3):491-495. doi: 10.1097/TA.0000000000001565. J Trauma Acute Care Surg. 2017. PMID: 28590356 Free PMC article.
All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.
Reisz JA, Wither MJ, Moore EE, Slaughter AL, Moore HB, Ghasabyan A, Chandler J, Schaub LJ, Fragoso M, Nunns G, Silliman CC, Hansen KC, Banerjee A, Sheppard FR, D'Alessandro A. Reisz JA, et al. Among authors: wither mj. J Trauma Acute Care Surg. 2018 Mar;84(3):537-541. doi: 10.1097/TA.0000000000001721. J Trauma Acute Care Surg. 2018. PMID: 29112093 Free PMC article.
Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements.
Clendenen N, Nunns GR, Moore EE, Gonzalez E, Chapman M, Reisz JA, Peltz E, Fragoso M, Nemkov T, Wither MJ, Sauaia A, Silliman CC, Hansen K, Banerjee A, D'Alessandro A, Moore HB. Clendenen N, et al. Among authors: wither mj. Blood Transfus. 2019 Sep;17(5):347-356. doi: 10.2450/2018.0188-18. Epub 2018 Dec 13. Blood Transfus. 2019. PMID: 30747701 Free PMC article.
Early hemorrhage triggers metabolic responses that build up during prolonged shock.
D'Alessandro A, Moore HB, Moore EE, Wither M, Nemkov T, Gonzalez E, Slaughter A, Fragoso M, Hansen KC, Silliman CC, Banerjee A. D'Alessandro A, et al. Am J Physiol Regul Integr Comp Physiol. 2015 Jun 15;308(12):R1034-44. doi: 10.1152/ajpregu.00030.2015. Epub 2015 Apr 15. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 25876652 Free PMC article.
Omics markers of the red cell storage lesion and metabolic linkage.
D'alessandro A, Nemkov T, Reisz J, Dzieciatkowska M, Wither MJ, Hansen KC. D'alessandro A, et al. Among authors: wither mj. Blood Transfus. 2017 Mar;15(2):137-144. doi: 10.2450/2017.0341-16. Blood Transfus. 2017. PMID: 28263171 Free PMC article. Review.
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