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TRPML1: an ion channel in the lysosome.
Wang W, Zhang X, Gao Q, Xu H. Wang W, et al. Among authors: gao q. Handb Exp Pharmacol. 2014;222:631-45. doi: 10.1007/978-3-642-54215-2_24. Handb Exp Pharmacol. 2014. PMID: 24756723 Review.
A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis.
Samie M, Wang X, Zhang X, Goschka A, Li X, Cheng X, Gregg E, Azar M, Zhuo Y, Garrity AG, Gao Q, Slaugenhaupt S, Pickel J, Zolov SN, Weisman LS, Lenk GM, Titus S, Bryant-Genevier M, Southall N, Juan M, Ferrer M, Xu H. Samie M, et al. Among authors: gao q. Dev Cell. 2013 Sep 16;26(5):511-24. doi: 10.1016/j.devcel.2013.08.003. Epub 2013 Aug 29. Dev Cell. 2013. PMID: 23993788 Free PMC article.
MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.
Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer M, Xu H. Zhang X, et al. Among authors: gao q. Nat Commun. 2016 Jun 30;7:12109. doi: 10.1038/ncomms12109. Nat Commun. 2016. PMID: 27357649 Free PMC article.
Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.
Zhang X, Chen W, Gao Q, Yang J, Yan X, Zhao H, Su L, Yang M, Gao C, Yao Y, Inoki K, Li D, Shao R, Wang S, Sahoo N, Kudo F, Eguchi T, Ruan B, Xu H. Zhang X, et al. Among authors: gao c, gao q. PLoS Biol. 2019 May 21;17(5):e3000252. doi: 10.1371/journal.pbio.3000252. eCollection 2019 May. PLoS Biol. 2019. PMID: 31112550 Free PMC article.
Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.
Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer M, Samuelson LC, Merchant JL, Xu H. Sahoo N, et al. Among authors: gao q. Dev Cell. 2017 May 8;41(3):262-273.e6. doi: 10.1016/j.devcel.2017.04.003. Dev Cell. 2017. PMID: 28486130 Free PMC article.
9,540 results