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Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy.
Nübling G, Schuberth M, Feldmer K, Giese A, Holdt LM, Teupser D, Lorenzl S. Nübling G, et al. Among authors: lorenzl s. Exp Brain Res. 2017 Aug;235(8):2407-2412. doi: 10.1007/s00221-017-4978-4. Epub 2017 May 10. Exp Brain Res. 2017. PMID: 28493068
Which ante mortem clinical features predict progressive supranuclear palsy pathology?
Respondek G, Kurz C, Arzberger T, Compta Y, Englund E, Ferguson LW, Gelpi E, Giese A, Irwin DJ, Meissner WG, Nilsson C, Pantelyat A, Rajput A, van Swieten JC, Troakes C, Josephs KA, Lang AE, Mollenhauer B, Müller U, Whitwell JL, Antonini A, Bhatia KP, Bordelon Y, Corvol JC, Colosimo C, Dodel R, Grossman M, Kassubek J, Krismer F, Levin J, Lorenzl S, Morris H, Nestor P, Oertel WH, Rabinovici GD, Rowe JB, van Eimeren T, Wenning GK, Boxer A, Golbe LI, Litvan I, Stamelou M, Höglinger GU; Movement Disorder Society-Endorsed PSP Study Group. Respondek G, et al. Among authors: lorenzl s. Mov Disord. 2017 Jul;32(7):995-1005. doi: 10.1002/mds.27034. Epub 2017 May 13. Mov Disord. 2017. PMID: 28500752 Free PMC article. Review.
Increased prevalence of bladder and intestinal dysfunction in amyotrophic lateral sclerosis.
Nübling GS, Mie E, Bauer RM, Hensler M, Lorenzl S, Hapfelmeier A, Irwin DE, Borasio GD, Winkler AS. Nübling GS, et al. Among authors: lorenzl s. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Jun;15(3-4):174-9. doi: 10.3109/21678421.2013.868001. Epub 2014 Jan 31. Amyotroph Lateral Scler Frontotemporal Degener. 2014. PMID: 24479577
The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.
Levin J, Maaß S, Schuberth M, Respondek G, Paul F, Mansmann U, Oertel WH, Lorenzl S, Krismer F, Seppi K, Poewe W, Wenning G; PROMESA study group; Giese A, Bötzel K, Höglinger G. Levin J, et al. Among authors: lorenzl s. J Neural Transm (Vienna). 2016 Apr;123(4):439-45. doi: 10.1007/s00702-016-1507-8. Epub 2016 Jan 25. J Neural Transm (Vienna). 2016. PMID: 26809243 Clinical Trial.
170 results