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Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties.
Mahrouf-Yorgov M, Augeul L, Da Silva CC, Jourdan M, Rigolet M, Manin S, Ferrera R, Ovize M, Henry A, Guguin A, Meningaud JP, Dubois-Randé JL, Motterlini R, Foresti R, Rodriguez AM. Mahrouf-Yorgov M, et al. Cell Death Differ. 2017 Jul;24(7):1224-1238. doi: 10.1038/cdd.2017.51. Epub 2017 May 19. Cell Death Differ. 2017. PMID: 28524859 Free PMC article.
Lung fibroblasts share mesenchymal stem cell features which are altered in chronic obstructive pulmonary disease via the overactivation of the Hedgehog signaling pathway.
Figeac F, Dagouassat M, Mahrouf-Yorgov M, Le Gouvello S, Trébeau C, Sayed A, Stern JB, Validire P, Dubois-Randé JL, Boczkowski J, Mus-Veteau I, Rodriguez AM. Figeac F, et al. PLoS One. 2015 Mar 27;10(3):e0121579. doi: 10.1371/journal.pone.0121579. eCollection 2015. PLoS One. 2015. PMID: 25815884 Free PMC article.
367 results