Howard KA - Search Results

1

Albumin-based drug delivery using cysteine 34 chemical conjugates - important considerations and requirements.

Caspersen MB, Kuhlmann M, Nicholls K, Saxton MJ, Andersen B, Bunting K, Cameron J, Howard KA. Caspersen MB, et al. Among authors: howard ka. Ther Deliv. 2017 Jul;8(7):511-519. doi: 10.4155/tde-2017-0038. Epub 2017 May 30. Ther Deliv. 2017. PMID: 28555530

2

Delivery of RNA interference therapeutics using polycation-based nanoparticles.

Howard KA. Howard KA. Adv Drug Deliv Rev. 2009 Jul 25;61(9):710-20. doi: 10.1016/j.addr.2009.04.001. Epub 2009 Apr 5. Adv Drug Deliv Rev. 2009. PMID: 19356738 Review.

3

Polycation-based nanoparticle delivery of RNAi therapeutics: adverse effects and solutions.

Ballarín-González B, Howard KA. Ballarín-González B, et al. Among authors: howard ka. Adv Drug Deliv Rev. 2012 Dec;64(15):1717-29. doi: 10.1016/j.addr.2012.07.004. Epub 2012 Jul 16. Adv Drug Deliv Rev. 2012. PMID: 22800620 Review.

4

Albumin: the next-generation delivery technology.

Howard KA. Howard KA. Ther Deliv. 2015 Mar;6(3):265-8. doi: 10.4155/tde.14.124. Ther Deliv. 2015. PMID: 25853301 No abstract available.

5

Neonatal Fc Receptor Binding Tolerance toward the Covalent Conjugation of Payloads to Cysteine 34 of Human Albumin Variants.

Petersen SS, Kläning E, Ebbesen MF, Andersen B, Cameron J, Sørensen ES, Howard KA. Petersen SS, et al. Among authors: howard ka. Mol Pharm. 2016 Feb 1;13(2):677-82. doi: 10.1021/acs.molpharmaceut.5b00605. Epub 2015 Dec 29. Mol Pharm. 2016. PMID: 26654692

6

Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs.

Viuff D, Antunes F, Evans L, Cameron J, Dyrnesli H, Thue Ravn B, Stougaard M, Thiam K, Andersen B, Kjærulff S, Howard KA. Viuff D, et al. Among authors: howard ka. J Control Release. 2016 Feb 10;223:22-30. doi: 10.1016/j.jconrel.2015.12.019. Epub 2015 Dec 14. J Control Release. 2016. PMID: 26699424

7

Albumin-based drug delivery: harnessing nature to cure disease.

Larsen MT, Kuhlmann M, Hvam ML, Howard KA. Larsen MT, et al. Among authors: howard ka. Mol Cell Ther. 2016 Feb 27;4:3. doi: 10.1186/s40591-016-0048-8. eCollection 2016. Mol Cell Ther. 2016. PMID: 26925240 Free PMC article. Review.

8

An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing.

Bienk K, Hvam ML, Pakula MM, Dagnæs-Hansen F, Wengel J, Malle BM, Kragh-Hansen U, Cameron J, Bukrinski JT, Howard KA. Bienk K, et al. Among authors: howard ka. J Control Release. 2016 Jun 28;232:143-51. doi: 10.1016/j.jconrel.2016.04.013. Epub 2016 Apr 12. J Control Release. 2016. PMID: 27084489

9

Site-selective conjugation of an anticoagulant aptamer to recombinant albumins and maintenance of neonatal Fc receptor binding.

Schmøkel J, Voldum A, Tsakiridou G, Kuhlmann M, Cameron J, Sørensen ES, Wengel J, Howard KA. Schmøkel J, et al. Among authors: howard ka. Nanotechnology. 2017 May 19;28(20):204004. doi: 10.1088/1361-6528/aa6a9b. Epub 2017 Mar 31. Nanotechnology. 2017. PMID: 28362634

10

Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin.

Schmidt EGW, Hvam ML, Antunes F, Cameron J, Viuff D, Andersen B, Kristensen NN, Howard KA. Schmidt EGW, et al. Among authors: howard ka. J Biol Chem. 2017 Aug 11;292(32):13312-13322. doi: 10.1074/jbc.M117.794248. Epub 2017 Jun 21. J Biol Chem. 2017. PMID: 28637874 Free PMC article.

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