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Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.
Dalva M, El Jellas K, Steine SJ, Johansson BB, Ringdal M, Torsvik J, Immervoll H, Hoem D, Laemmerhirt F, Simon P, Lerch MM, Johansson S, Njølstad PR, Weiss FU, Fjeld K, Molven A. Dalva M, et al. Among authors: hoem d. Pancreatology. 2017 Jan-Feb;17(1):83-88. doi: 10.1016/j.pan.2016.10.006. Epub 2016 Oct 11. Pancreatology. 2017. PMID: 27773618
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants.
El Jellas K, Johansson BB, Fjeld K, Antonopoulos A, Immervoll H, Choi MH, Hoem D, Lowe ME, Lombardo D, Njølstad PR, Dell A, Mas E, Haslam SM, Molven A. El Jellas K, et al. Among authors: hoem d. J Biol Chem. 2018 Dec 14;293(50):19476-19491. doi: 10.1074/jbc.RA118.001934. Epub 2018 Oct 12. J Biol Chem. 2018. PMID: 30315106 Free PMC article.
Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis.
Fjeld K, Masson E, Lin JH, Michl P, Stokowy T, Gravdal A, El Jellas K, Steine SJ, Hoem D, Johansson BB, Dalva M, Ruffert C, Zou WB, Li ZS, Njølstad PR, Chen JM, Liao Z, Johansson S, Rosendahl J, Férec C, Molven A. Fjeld K, et al. Among authors: hoem d. Pancreatology. 2020 Apr;20(3):377-384. doi: 10.1016/j.pan.2020.01.011. Epub 2020 Jan 20. Pancreatology. 2020. PMID: 32007358
37 results