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Page 1
Decreased expression of Klotho in cardiac atria biopsy samples from patients at higher risk of atherosclerotic cardiovascular disease.
Corsetti G, Pasini E, Scarabelli TM, Romano C, Agrawal PR, Chen-Scarabelli C, Knight R, Saravolatz L, Narula J, Ferrari-Vivaldi M, Flati V, Assanelli D, Dioguardi FS. Corsetti G, et al. Among authors: knight r. J Geriatr Cardiol. 2016 Aug;13(8):701-711. doi: 10.11909/j.issn.1671-5411.2016.08.009. J Geriatr Cardiol. 2016. PMID: 27781061 Free PMC article.
Urocortin Induces Phosphorylation of Distinct Residues of Signal Transducer and Activator of Transcription 3 (STAT3) via Different Signaling Pathways.
Corsetti G, Yuan Z, Romano C, Chen-Scarabelli C, Fanzani A, Pasini E, Dioguardi FS, Onorati F, Linardi D, Knight R, Patel H, Faggian G, Saravolatz L, Scarabelli TM. Corsetti G, et al. Among authors: knight r. Med Sci Monit Basic Res. 2019 May 10;25:139-152. doi: 10.12659/MSMBR.914611. Med Sci Monit Basic Res. 2019. PMID: 31073117 Free PMC article.
Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO.
Scarabelli TM, Stephanou A, Pasini E, Gitti G, Townsend P, Lawrence K, Chen-Scarabelli C, Saravolatz L, Latchman D, Knight R, Gardin J. Scarabelli TM, et al. Among authors: knight r. J Am Coll Cardiol. 2004 Mar 3;43(5):865-74. doi: 10.1016/j.jacc.2003.09.050. J Am Coll Cardiol. 2004. PMID: 14998631 Free article.
Urocortins: take them to heart.
Scarabelli T, Knight R. Scarabelli T, et al. Among authors: knight r. Curr Med Chem Cardiovasc Hematol Agents. 2004 Oct;2(4):335-342. doi: 10.2174/1568016043356174. Curr Med Chem Cardiovasc Hematol Agents. 2004. PMID: 15320777 Review.
The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway.
Chen-Scarabelli C, Saravolatz Ii L, McCaukey R, Scarabelli G, Di Rezze J, Mohanty B, Barry S, Latchman D, Georgiadis V, McCormick J, Saravolatz L, Knight R, Faggian G, Narula J, Stephanou A, Scarabelli TM. Chen-Scarabelli C, et al. Among authors: knight r. JAKSTAT. 2013 Jul 1;2(3):e24812. doi: 10.4161/jkst.24812. Epub 2013 May 7. JAKSTAT. 2013. PMID: 24069562 Free PMC article.
Diabetic hearts have lower basal urocortin levels that fail to increase after cardioplegic arrest: association with increased apoptosis and postsurgical cardiac dysfunction.
Chen-Scarabelli C, Knight R, Stephanou A, Scarabelli G, Onorati F, Tessari M, Rungatscher A, Narula J, Saravolatz L, Mazzucco A, Faggian G, Scarabelli TM. Chen-Scarabelli C, et al. Among authors: knight r. J Thorac Cardiovasc Surg. 2014 Nov;148(5):2296-308. doi: 10.1016/j.jtcvs.2014.05.018. Epub 2014 May 14. J Thorac Cardiovasc Surg. 2014. PMID: 24954177 Free article.
Activation of Src protein tyrosine kinase plays an essential role in urocortin-mediated cardioprotection.
Yuan Z, McCauley R, Chen-Scarabelli C, Abounit K, Stephanou A, Barry SP, Knight R, Saravolatz SF, Saravolatz LD, Ulgen BO, Scarabelli GM, Faggian G, Mazzucco A, Saravolatz L, Scarabelli TM. Yuan Z, et al. Among authors: knight r. Mol Cell Endocrinol. 2010 Aug 30;325(1-2):1-7. doi: 10.1016/j.mce.2010.04.013. Epub 2010 Apr 21. Mol Cell Endocrinol. 2010. PMID: 20416357
3,437 results