Kozhich AT - Search Results

1

A multiplexed immunocapture liquid chromatography tandem mass spectrometry assay for the simultaneous measurement of myostatin and GDF-11 in rat serum using an automated sample preparation platform.

Zhao Y, Liu G, Zambito FC, Zhang YJ, DeSilva BS, Kozhich AT, Shen JX. Zhao Y, et al. Among authors: kozhich at. Anal Chim Acta. 2017 Aug 1;979:36-44. doi: 10.1016/j.aca.2017.04.028. Epub 2017 Apr 26. Anal Chim Acta. 2017. PMID: 28599707

2

Targeting an acid labile aspartyl-prolyl amide bond as a viable alternative to trypsin digestion to generate a surrogate peptide for LC-MS/MS analysis.

Fung EN, Zambito F, Haulenbeek J, Piccoli SP, Zhang Y, DeSilva B, Arnold M, Kozhich A. Fung EN, et al. Bioanalysis. 2014;6(22):2985-98. doi: 10.4155/bio.14.182. Bioanalysis. 2014. PMID: 25496253

3

An integrated multiplatform bioanalytical strategy for antibody-drug conjugates: a novel case study.

Myler H, Rangan VS, Wang J, Kozhich A, Cummings JA, Neely R, Dail D, Liu A, Wang B, Vezina HE, Freebern W, Sung MC, Passmore D, Deshpande S, Kempe T, Gu H, Saewert M, Manney A, Lute J, Zambito F, Wong RL, Piccoli SP, Aubry AF, Pillutla R, Arnold M, DeSilva B. Myler H, et al. Bioanalysis. 2015;7(13):1569-82. doi: 10.4155/bio.15.80. Bioanalysis. 2015. PMID: 26226308

4

Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC-MS/MS approach: Assay development, validation, and a case study.

Liu A, Kozhich A, Passmore D, Gu H, Wong R, Zambito F, Rangan VS, Myler H, Aubry AF, Arnold ME, Wang J. Liu A, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:54-62. doi: 10.1016/j.jchromb.2015.08.007. Epub 2015 Aug 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26310897

5

LC-MS/MS multiplexed assay for the quantitation of a therapeutic protein BMS-986089 and the target protein Myostatin.

Zhu Y, D'Arienzo C, Lou Z, Kozhich A, Madireddi M, Chimalakonda A, Tymiak A, Olah TV. Zhu Y, et al. Bioanalysis. 2016 Feb;8(3):193-204. doi: 10.4155/bio.15.238. Epub 2016 Jan 26. Bioanalysis. 2016. PMID: 26811930

6

Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody-drug conjugates in biological matrices.

Myler H, Rangan VS, Kozhich A, Hoffpauir B, Dail D, Cummings J, Saewert M, Manney A, Liu A, Rao C, Wang J, Pillutla R, DeSilva B. Myler H, et al. Bioanalysis. 2016 Mar;8(6):519-31. doi: 10.4155/bio.16.13. Epub 2016 Feb 26. Bioanalysis. 2016. PMID: 26915587

7

Techniques for quantitative LC-MS/MS analysis of protein therapeutics: advances in enzyme digestion and immunocapture.

Fung EN, Bryan P, Kozhich A. Fung EN, et al. Bioanalysis. 2016 Apr;8(8):847-56. doi: 10.4155/bio.16.24. Epub 2016 Mar 23. Bioanalysis. 2016. PMID: 27005854 Review.

8

Antibody-drug conjugate bioanalysis using LB-LC-MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays.

Wang J, Gu H, Liu A, Kozhich A, Rangan V, Myler H, Luo L, Wong R, Sun H, Wang B, Vezina HE, Deshpande S, Zhang Y, Yang Z, Olah TV, Aubry AF, Arnold ME, Pillutla R, DeSilva B. Wang J, et al. Bioanalysis. 2016 Jul;8(13):1383-401. doi: 10.4155/bio-2016-0017. Epub 2016 Jun 9. Bioanalysis. 2016. PMID: 27277879

9

Singlicate Ligand Binding Assay Using an Automated Microfluidic System: a Clinical Case Study.

Jiang H, Kozhich A, Cummings J, Gambardella J, Zambito F, Titsch C, Haulenbeek J, Phillips K, Fergus R, Myler H. Jiang H, et al. AAPS J. 2017 Sep;19(5):1461-1468. doi: 10.1208/s12248-017-0105-5. Epub 2017 Jun 6. AAPS J. 2017. PMID: 28589510

10

Surface plasmon resonance as a tool for ligand-binding assay reagent characterization in bioanalysis of biotherapeutics.

Duo J, Bruno J, Kozhich A, David-Brown D, Luo L, Kwok S, Santockyte R, Haulenbeek J, Liu R, Hamuro L, Peterson JE, Piccoli S, DeSilva B, Pillutla R, Zhang YJ. Duo J, et al. Bioanalysis. 2018 Apr 1;10(8):559-576. doi: 10.4155/bio-2017-0271. Epub 2018 Apr 27. Bioanalysis. 2018. PMID: 29701071

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