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Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction.
De Pauw A, Andre E, Sekkali B, Bouzin C, Esfahani H, Barbier N, Loriot A, De Smet C, Vanhoutte L, Moniotte S, Gerber B, di Mauro V, Catalucci D, Feron O, Hilfiker-Kleiner D, Balligand JL. De Pauw A, et al. JCI Insight. 2017 Jun 15;2(12):e91810. doi: 10.1172/jci.insight.91810. eCollection 2017 Jun 15. JCI Insight. 2017. PMID: 28614798 Free PMC article.
Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade.
Sorrentino SA, Doerries C, Manes C, Speer T, Dessy C, Lobysheva I, Mohmand W, Akbar R, Bahlmann F, Besler C, Schaefer A, Hilfiker-Kleiner D, Lüscher TF, Balligand JL, Drexler H, Landmesser U. Sorrentino SA, et al. J Am Coll Cardiol. 2011 Feb 1;57(5):601-11. doi: 10.1016/j.jacc.2010.09.037. J Am Coll Cardiol. 2011. PMID: 21272752 Free article.
Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.
Hoch M, Fischer P, Stapel B, Missol-Kolka E, Sekkali B, Scherr M, Favret F, Braun T, Eder M, Schuster-Gossler K, Gossler A, Hilfiker A, Balligand JL, Drexler H, Hilfiker-Kleiner D. Hoch M, et al. Cell Stem Cell. 2011 Aug 5;9(2):131-43. doi: 10.1016/j.stem.2011.07.001. Cell Stem Cell. 2011. PMID: 21816364 Free article.
HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome.
Hermida N, Markl A, Hamelet J, Van Assche T, Vanderper A, Herijgers P, van Bilsen M, Hilfiker-Kleiner D, Noppe G, Beauloye C, Horman S, Balligand JL. Hermida N, et al. Cardiovasc Res. 2013 Jul 1;99(1):44-54. doi: 10.1093/cvr/cvt070. Epub 2013 Mar 29. Cardiovasc Res. 2013. PMID: 23542580
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL. Belge C, et al. Circulation. 2014 Jan 28;129(4):451-62. doi: 10.1161/CIRCULATIONAHA.113.004940. Epub 2013 Nov 4. Circulation. 2014. PMID: 24190960
An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.
Lourenço AP, Leite-Moreira AF, Balligand JL, Bauersachs J, Dawson D, de Boer RA, de Windt LJ, Falcão-Pires I, Fontes-Carvalho R, Franz S, Giacca M, Hilfiker-Kleiner D, Hirsch E, Maack C, Mayr M, Pieske B, Thum T, Tocchetti CG, Brutsaert DL, Heymans S. Lourenço AP, et al. Eur J Heart Fail. 2018 Feb;20(2):216-227. doi: 10.1002/ejhf.1059. Epub 2017 Nov 16. Eur J Heart Fail. 2018. PMID: 29148148 Free article. Review.
The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.
Frantz S, Falcao-Pires I, Balligand JL, Bauersachs J, Brutsaert D, Ciccarelli M, Dawson D, de Windt LJ, Giacca M, Hamdani N, Hilfiker-Kleiner D, Hirsch E, Leite-Moreira A, Mayr M, Thum T, Tocchetti CG, van der Velden J, Varricchi G, Heymans S. Frantz S, et al. Eur J Heart Fail. 2018 Mar;20(3):445-459. doi: 10.1002/ejhf.1138. Epub 2018 Jan 15. Eur J Heart Fail. 2018. PMID: 29333691 Free PMC article. Review.
Metabolic changes in hypertrophic cardiomyopathies: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology.
van der Velden J, Tocchetti CG, Varricchi G, Bianco A, Sequeira V, Hilfiker-Kleiner D, Hamdani N, Leite-Moreira AF, Mayr M, Falcão-Pires I, Thum T, Dawson DK, Balligand JL, Heymans S. van der Velden J, et al. Cardiovasc Res. 2018 Aug 1;114(10):1273-1280. doi: 10.1093/cvr/cvy147. Cardiovasc Res. 2018. PMID: 29912308 Free PMC article. Review.
Treatments targeting inotropy.
Maack C, Eschenhagen T, Hamdani N, Heinzel FR, Lyon AR, Manstein DJ, Metzger J, Papp Z, Tocchetti CG, Yilmaz MB, Anker SD, Balligand JL, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland JG, de Boer RA, Dietl A, Fischmeister R, Harjola VP, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke WA, Lund LH, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristić A, Ruschitzka F, Seferović PM, Skouri H, Zimmermann WH, Mebazaa A. Maack C, et al. Eur Heart J. 2019 Nov 21;40(44):3626-3644. doi: 10.1093/eurheartj/ehy600. Eur Heart J. 2019. PMID: 30295807 Free PMC article.
Increased prostaglandin-D2 in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation.
Stelling E, Ricke-Hoch M, Erschow S, Hoffmann S, Bergmann AK, Heimerl M, Pietzsch S, Battmer K, Haase A, Stapel B, Scherr M, Balligand JL, Binah O, Hilfiker-Kleiner D. Stelling E, et al. PLoS Biol. 2020 Dec 28;18(12):e3000739. doi: 10.1371/journal.pbio.3000739. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33370269 Free PMC article.
232 results