Blundell PA - Search Results

1

Engineering the fragment crystallizable (Fc) region of human IgG1 multimers and monomers to fine-tune interactions with sialic acid-dependent receptors.

Blundell PA, Le NPL, Allen J, Watanabe Y, Pleass RJ. Blundell PA, et al. J Biol Chem. 2017 Aug 4;292(31):12994-13007. doi: 10.1074/jbc.M117.795047. Epub 2017 Jun 15. J Biol Chem. 2017. PMID: 28620050 Free PMC article.

2

A Method to Detect the Binding of Hyper-Glycosylated Fragment Crystallizable (Fc) Region of Human IgG1 to Glycan Receptors.

Blundell P, Pleass R. Blundell P, et al. Methods Mol Biol. 2019;1904:417-421. doi: 10.1007/978-1-4939-8958-4_20. Methods Mol Biol. 2019. PMID: 30539483

3

Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization.

Foss S, Grevys A, Sand KMK, Bern M, Blundell P, Michaelsen TE, Pleass RJ, Sandlie I, Andersen JT. Foss S, et al. J Control Release. 2016 Feb 10;223:42-52. doi: 10.1016/j.jconrel.2015.12.033. Epub 2015 Dec 21. J Control Release. 2016. PMID: 26718855

4

Insertion of N-Terminal Hinge Glycosylation Enhances Interactions of the Fc Region of Human IgG1 Monomers with Glycan-Dependent Receptors and Blocks Hemagglutination by the Influenza Virus.

Blundell PA, Lu D, Wilkinson M, Dell A, Haslam S, Pleass RJ. Blundell PA, et al. J Immunol. 2019 Mar 1;202(5):1595-1611. doi: 10.4049/jimmunol.1801337. Epub 2019 Jan 25. J Immunol. 2019. PMID: 30683699 Free PMC article.

5

Choice of Host Cell Line Is Essential for the Functional Glycosylation of the Fc Region of Human IgG1 Inhibitors of Influenza B Viruses.

Blundell PA, Lu D, Dell A, Haslam S, Pleass RJ. Blundell PA, et al. J Immunol. 2020 Feb 15;204(4):1022-1034. doi: 10.4049/jimmunol.1901145. Epub 2020 Jan 6. J Immunol. 2020. PMID: 31907284 Free PMC article.

6

Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination.

Baksmeier C, Blundell P, Steckel J, Schultz V, Gu Q, Da Silva Filipe A, Kohl A, Linnington C, Lu D, Dell A, Haslam S, Wang J, Czajkowsky D, Goebels N, Pleass RJ. Baksmeier C, et al. Immunology. 2021 Sep;164(1):90-105. doi: 10.1111/imm.13341. Epub 2021 May 9. Immunology. 2021. PMID: 33880776 Free PMC article.

7

Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications.

Czajkowsky DM, Andersen JT, Fuchs A, Wilson TJ, Mekhaiel D, Colonna M, He J, Shao Z, Mitchell DA, Wu G, Dell A, Haslam S, Lloyd KA, Moore SC, Sandlie I, Blundell PA, Pleass RJ. Czajkowsky DM, et al. Among authors: blundell pa. Sci Rep. 2015 Apr 27;5:9526. doi: 10.1038/srep09526. Sci Rep. 2015. PMID: 25912958 Free PMC article.

8

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms.

Alomran N, Blundell P, Alsolaiss J, Crittenden E, Ainsworth S, Dawson CA, Edge RJ, Hall SR, Harrison RA, Wilkinson MC, Menzies SK, Casewell NR. Alomran N, et al. Toxins (Basel). 2022 Jun 29;14(7):443. doi: 10.3390/toxins14070443. Toxins (Basel). 2022. PMID: 35878181 Free PMC article.

9

Transfection of the African and American trypanosomes.

Kelly JM, Taylor MC, Rudenko G, Blundell PA. Kelly JM, et al. Among authors: blundell pa. Methods Mol Biol. 1995;47:349-59. doi: 10.1385/0-89603-310-4:349. Methods Mol Biol. 1995. PMID: 7550751 No abstract available.

10

Control of antigenic variation in African trypanosomes.

Borst P, Gommers-Ampt JH, Ligtenberg MJ, Rudenko G, Kieft R, Taylor MC, Blundell PA, van Leeuwen F. Borst P, et al. Among authors: blundell pa. Cold Spring Harb Symp Quant Biol. 1993;58:105-14. doi: 10.1101/sqb.1993.058.01.014. Cold Spring Harb Symp Quant Biol. 1993. PMID: 7956020 Review. No abstract available.

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