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Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.
Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ. Wynn JL, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2627-35. doi: 10.1073/pnas.1515793113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114524 Free PMC article.
Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis.
Meegan JE, Shaver CM, Putz ND, Jesse JJ, Landstreet SR, Lee HNR, Sidorova TN, McNeil JB, Wynn JL, Cheung-Flynn J, Komalavilas P, Brophy CM, Ware LB, Bastarache JA. Meegan JE, et al. Among authors: wynn jl. PLoS One. 2020 Feb 3;15(2):e0228727. doi: 10.1371/journal.pone.0228727. eCollection 2020. PLoS One. 2020. PMID: 32012200 Free PMC article.
Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality.
Wynn JL, Scumpia PO, Stocks BT, Romano-Keeler J, Alrifai MW, Liu JH, Kim AS, Alford CE, Matta P, Weitkamp JH, Moore DJ. Wynn JL, et al. J Immunol. 2015 Aug 1;195(3):1064-70. doi: 10.4049/jimmunol.1500771. Epub 2015 Jun 22. J Immunol. 2015. PMID: 26101326 Free PMC article.
Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model.
Atkinson SJ, Varisco BM, Sandquist M, Daly MN, Klingbeil L, Kuethe JW, Midura EF, Harmon K, Opaka A, Lahni P, Piraino G, Hake P, Zingarelli B, Mortenson JE, Wynn JL, Wong HR. Atkinson SJ, et al. Among authors: wynn jl. Mol Med. 2016 Oct;22:455-463. doi: 10.2119/molmed.2016.00058. Epub 2016 Aug 8. Mol Med. 2016. PMID: 27506554 Free PMC article.
126 results