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Nutrition modulation of human aging: The calorie restriction paradigm.
Das SK, Balasubramanian P, Weerasekara YK. Das SK, et al. Among authors: balasubramanian p. Mol Cell Endocrinol. 2017 Nov 5;455:148-157. doi: 10.1016/j.mce.2017.04.011. Epub 2017 Apr 12. Mol Cell Endocrinol. 2017. PMID: 28412520 Free PMC article. Review.
Growth factors, aging and age-related diseases.
Balasubramanian P, Longo VD. Balasubramanian P, et al. Growth Horm IGF Res. 2016 Jun;28:66-8. doi: 10.1016/j.ghir.2016.01.001. Epub 2016 Jan 7. Growth Horm IGF Res. 2016. PMID: 26883276 Free PMC article.
Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases.
Ungvari Z, Tarantini S, Nyúl-Tóth Á, Kiss T, Yabluchanskiy A, Csipo T, Balasubramanian P, Lipecz A, Benyo Z, Csiszar A. Ungvari Z, et al. Among authors: balasubramanian p. Geroscience. 2019 Dec;41(6):727-738. doi: 10.1007/s11357-019-00107-w. Epub 2019 Oct 26. Geroscience. 2019. PMID: 31655958 Free PMC article. Review.
Linking Klotho, Nrf2, MAP kinases and aging.
Balasubramanian P, Longo VD. Balasubramanian P, et al. Aging (Albany NY). 2010 Oct;2(10):632-3. doi: 10.18632/aging.100219. Aging (Albany NY). 2010. PMID: 21076180 Free PMC article. No abstract available.
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans.
Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P, Longo VD. Guevara-Aguirre J, et al. Among authors: balasubramanian p. Sci Transl Med. 2011 Feb 16;3(70):70ra13. doi: 10.1126/scitranslmed.3001845. Sci Transl Med. 2011. PMID: 21325617 Free PMC article.
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.
Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD. Levine ME, et al. Among authors: balasubramanian p. Cell Metab. 2014 Mar 4;19(3):407-17. doi: 10.1016/j.cmet.2014.02.006. Cell Metab. 2014. PMID: 24606898 Free PMC article.
474 results