Saavedra JE - Search Results

1

The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation.

Heckler M, Osterberg N, Guenzle J, Thiede-Stan NK, Reichardt W, Weidensteiner C, Saavedra JE, Weyerbrock A. Heckler M, et al. Among authors: saavedra je. Tumour Biol. 2017 Jun;39(6):1010428317703922. doi: 10.1177/1010428317703922. Tumour Biol. 2017. PMID: 28653883 Free article.

2

Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-π-activated nitric oxide donor PABA/NO in malignant gliomas.

Kogias E, Osterberg N, Baumer B, Psarras N, Koentges C, Papazoglou A, Saavedra JE, Keefer LK, Weyerbrock A. Kogias E, et al. Among authors: saavedra je. Int J Cancer. 2012 Mar 1;130(5):1184-94. doi: 10.1002/ijc.26106. Epub 2011 Jul 21. Int J Cancer. 2012. PMID: 21455987 Free PMC article.

3

JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas.

Weyerbrock A, Osterberg N, Psarras N, Baumer B, Kogias E, Werres A, Bette S, Saavedra JE, Keefer LK, Papazoglou A. Weyerbrock A, et al. Among authors: saavedra je. Neurosurgery. 2012 Feb;70(2):497-510; discussion 510. doi: 10.1227/NEU.0b013e31823209cf. Neurosurgery. 2012. PMID: 21849924 Free PMC article.

4

Effects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI.

Weidensteiner C, Reichardt W, Shami PJ, Saavedra JE, Keefer LK, Baumer B, Werres A, Jasinski R, Osterberg N, Weyerbrock A. Weidensteiner C, et al. Among authors: saavedra je. Nitric Oxide. 2013 Apr 1;30:17-25. doi: 10.1016/j.niox.2013.01.003. Epub 2013 Jan 28. Nitric Oxide. 2013. PMID: 23370169 Free PMC article.

5

Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme.

Günzle J, Osterberg N, Saavedra JE, Weyerbrock A. Günzle J, et al. Among authors: saavedra je. Cell Death Dis. 2016 Sep 1;7(9):e2349. doi: 10.1038/cddis.2016.254. Cell Death Dis. 2016. PMID: 27584787 Free PMC article.

6

ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma.

Guenzle J, Wolf LJ, Garrelfs NW, Goeldner JM, Osterberg N, Schindler CR, Saavedra JE, Weyerbrock A. Guenzle J, et al. Among authors: saavedra je. Cell Death Discov. 2017 Feb 27;3:17006. doi: 10.1038/cddiscovery.2017.6. eCollection 2017. Cell Death Discov. 2017. PMID: 28250971 Free PMC article.

7

Differential effects of nitric oxide on blood-brain barrier integrity and cerebral blood flow in intracerebral C6 gliomas.

Weyerbrock A, Walbridge S, Saavedra JE, Keefer LK, Oldfield EH. Weyerbrock A, et al. Among authors: saavedra je. Neuro Oncol. 2011 Feb;13(2):203-11. doi: 10.1093/neuonc/noq161. Epub 2010 Nov 1. Neuro Oncol. 2011. PMID: 21041233 Free PMC article.

8

Selective opening of the blood-tumor barrier by a nitric oxide donor and long-term survival in rats with C6 gliomas.

Weyerbrock A, Walbridge S, Pluta RM, Saavedra JE, Keefer LK, Oldfield EH. Weyerbrock A, et al. Among authors: saavedra je. J Neurosurg. 2003 Oct;99(4):728-37. doi: 10.3171/jns.2003.99.4.0728. J Neurosurg. 2003. PMID: 14567609

9

Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53.

Kitagaki J, Yang Y, Saavedra JE, Colburn NH, Keefer LK, Perantoni AO. Kitagaki J, et al. Among authors: saavedra je. Oncogene. 2009 Jan 29;28(4):619-24. doi: 10.1038/onc.2008.401. Epub 2008 Nov 3. Oncogene. 2009. PMID: 18978812 Free PMC article.

10

The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.

Maciag AE, Chakrapani H, Saavedra JE, Morris NL, Holland RJ, Kosak KM, Shami PJ, Anderson LM, Keefer LK. Maciag AE, et al. Among authors: saavedra je. J Pharmacol Exp Ther. 2011 Feb;336(2):313-20. doi: 10.1124/jpet.110.174904. Epub 2010 Oct 20. J Pharmacol Exp Ther. 2011. PMID: 20962031 Free PMC article.

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