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Page 1
Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.
Bolli MH, Abele S, Birker M, Bravo R, Bur D, de Kanter R, Kohl C, Grimont J, Hess P, Lescop C, Mathys B, Müller C, Nayler O, Rey M, Scherz M, Schmidt G, Seifert J, Steiner B, Velker J, Weller T. Bolli MH, et al. Among authors: de kanter r. J Med Chem. 2014 Jan 9;57(1):110-30. doi: 10.1021/jm4014696. Epub 2013 Dec 24. J Med Chem. 2014. PMID: 24367923
Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.
Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B. Bolli MH, et al. Among authors: de kanter r. Eur J Med Chem. 2016 Jun 10;115:326-41. doi: 10.1016/j.ejmech.2016.03.020. Epub 2016 Mar 12. Eur J Med Chem. 2016. PMID: 27027817
Macitentan does not interfere with hepatic bile salt transport.
Treiber A, Äänismaa P, de Kanter R, Delahaye S, Treher M, Hess P, Sidharta P. Treiber A, et al. Among authors: de kanter r. J Pharmacol Exp Ther. 2014 Jul;350(1):130-43. doi: 10.1124/jpet.114.214106. Epub 2014 Apr 25. J Pharmacol Exp Ther. 2014. PMID: 24769543 Free article. Clinical Trial.
The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468.
Treiber A, de Kanter R, Roch C, Gatfield J, Boss C, von Raumer M, Schindelholz B, Muehlan C, van Gerven J, Jenck F. Treiber A, et al. Among authors: de kanter r. J Pharmacol Exp Ther. 2017 Sep;362(3):489-503. doi: 10.1124/jpet.117.241596. Epub 2017 Jun 29. J Pharmacol Exp Ther. 2017. PMID: 28663311 Clinical Trial.
54 results