Kaplowitz N - Search Results

1

The role of MAP2 kinases and p38 kinase in acute murine liver injury models.

Zhang J, Min RWM, Le K, Zhou S, Aghajan M, Than TA, Win S, Kaplowitz N. Zhang J, et al. Among authors: kaplowitz n. Cell Death Dis. 2017 Jun 29;8(6):e2903. doi: 10.1038/cddis.2017.295. Cell Death Dis. 2017. PMID: 28661486 Free PMC article.

2

Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.

Shinohara M, Ybanez MD, Win S, Than TA, Jain S, Gaarde WA, Han D, Kaplowitz N. Shinohara M, et al. Among authors: kaplowitz n. J Biol Chem. 2010 Mar 12;285(11):8244-55. doi: 10.1074/jbc.M109.054999. Epub 2010 Jan 8. J Biol Chem. 2010. PMID: 20061376 Free PMC article.

3

c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice.

Win S, Than TA, Han D, Petrovic LM, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. J Biol Chem. 2011 Oct 7;286(40):35071-8. doi: 10.1074/jbc.M111.276089. Epub 2011 Aug 15. J Biol Chem. 2011. PMID: 21844199 Free PMC article.

4

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria.

Han D, Dara L, Win S, Than TA, Yuan L, Abbasi SQ, Liu ZX, Kaplowitz N. Han D, et al. Among authors: kaplowitz n. Trends Pharmacol Sci. 2013 Apr;34(4):243-53. doi: 10.1016/j.tips.2013.01.009. Epub 2013 Feb 28. Trends Pharmacol Sci. 2013. PMID: 23453390 Free PMC article. Review.

5

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.

Win S, Than TA, Le BH, García-Ruiz C, Fernandez-Checa JC, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. J Hepatol. 2015 Jun;62(6):1367-74. doi: 10.1016/j.jhep.2015.01.032. Epub 2015 Feb 7. J Hepatol. 2015. PMID: 25666017 Free PMC article.

6

c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src.

Win S, Than TA, Min RW, Aghajan M, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. Hepatology. 2016 Jun;63(6):1987-2003. doi: 10.1002/hep.28486. Epub 2016 Mar 15. Hepatology. 2016. PMID: 26845758 Free PMC article.

7

Antcin H Protects Against Acute Liver Injury Through Disruption of the Interaction of c-Jun-N-Terminal Kinase with Mitochondria.

Huo Y, Win S, Than TA, Yin S, Ye M, Hu H, Kaplowitz N. Huo Y, et al. Among authors: kaplowitz n. Antioxid Redox Signal. 2017 Feb 10;26(5):207-220. doi: 10.1089/ars.2016.6833. Epub 2016 Oct 11. Antioxid Redox Signal. 2017. PMID: 27596680 Free PMC article.

8

Protective role of p53 in acetaminophen hepatotoxicity.

Huo Y, Yin S, Yan M, Win S, Aung Than T, Aghajan M, Hu H, Kaplowitz N. Huo Y, et al. Among authors: kaplowitz n. Free Radic Biol Med. 2017 May;106:111-117. doi: 10.1016/j.freeradbiomed.2017.02.028. Epub 2017 Feb 11. Free Radic Biol Med. 2017. PMID: 28196650 Free PMC article.

9

New insights into the role and mechanism of c-Jun-N-terminal kinase signaling in the pathobiology of liver diseases.

Win S, Than TA, Zhang J, Oo C, Min RWM, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. Hepatology. 2018 May;67(5):2013-2024. doi: 10.1002/hep.29689. Epub 2018 Apr 6. Hepatology. 2018. PMID: 29194686 Free PMC article. Review.

10

The Regulation of JNK Signaling Pathways in Cell Death through the Interplay with Mitochondrial SAB and Upstream Post-Translational Effects.

Win S, Than TA, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. Int J Mol Sci. 2018 Nov 20;19(11):3657. doi: 10.3390/ijms19113657. Int J Mol Sci. 2018. PMID: 30463289 Free PMC article. Review.

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