Higgins GS - Search Results

1

TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy.

Pirovano G, Ashton TM, Herbert KJ, Bryant RJ, Verrill CL, Cerundolo L, Buffa FM, Prevo R, Harrap I, Ryan AJ, Macaulay V, McKenna WG, Higgins GS. Pirovano G, et al. Among authors: higgins gs. Br J Cancer. 2017 Aug 8;117(4):503-512. doi: 10.1038/bjc.2017.197. Epub 2017 Jul 4. Br J Cancer. 2017. PMID: 28677687 Free PMC article.

2

Conventional radiotherapy or hypofractionation? A study of molecular changes resulting from different radiation fractionation schemes.

Hamilton J, Higgins G, Bernhard EJ. Hamilton J, et al. Cancer Biol Ther. 2009 May;8(9):774-6. doi: 10.4161/cbt.8.9.8341. Epub 2009 May 4. Cancer Biol Ther. 2009. PMID: 19395860 Free article. No abstract available.

3

A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.

Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. Higgins GS, et al. Cancer Res. 2010 Apr 1;70(7):2984-93. doi: 10.1158/0008-5472.CAN-09-4040. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233878 Free PMC article.

4

Overexpression of POLQ confers a poor prognosis in early breast cancer patients.

Higgins GS, Harris AL, Prevo R, Helleday T, McKenna WG, Buffa FM. Higgins GS, et al. Oncotarget. 2010 Jul;1(3):175-84. doi: 10.18632/oncotarget.124. Oncotarget. 2010. PMID: 20700469 Free PMC article.

5

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.

Fokas E, Yoshimura M, Prevo R, Higgins G, Hackl W, Maira SM, Bernhard EJ, McKenna WG, Muschel RJ. Fokas E, et al. Radiat Oncol. 2012 Mar 27;7:48. doi: 10.1186/1748-717X-7-48. Radiat Oncol. 2012. PMID: 22452803 Free PMC article.

6

Drug radiotherapy combinations: review of previous failures and reasons for future optimism.

Higgins GS, O'Cathail SM, Muschel RJ, McKenna WG. Higgins GS, et al. Cancer Treat Rev. 2015 Feb;41(2):105-13. doi: 10.1016/j.ctrv.2014.12.012. Epub 2015 Jan 3. Cancer Treat Rev. 2015. PMID: 25579753 Review.

7

Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen.

Tiwana GS, Prevo R, Buffa FM, Yu S, Ebner DV, Howarth A, Folkes LK, Budwal B, Chu KY, Durrant L, Muschel RJ, McKenna WG, Higgins GS. Tiwana GS, et al. Among authors: higgins gs. Oncotarget. 2015 Mar 20;6(8):5978-89. doi: 10.18632/oncotarget.3468. Oncotarget. 2015. PMID: 25788274 Free PMC article.

8

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.

Ahrabi S, Sarkar S, Pfister SX, Pirovano G, Higgins GS, Porter AC, Humphrey TC. Ahrabi S, et al. Among authors: higgins gs. Nucleic Acids Res. 2016 Jul 8;44(12):5743-57. doi: 10.1093/nar/gkw326. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131361 Free PMC article.

9

Personalized Radiation Oncology: Epidermal Growth Factor Receptor and Other Receptor Tyrosine Kinase Inhibitors.

Higgins GS, Krause M, McKenna WG, Baumann M. Higgins GS, et al. Recent Results Cancer Res. 2016;198:107-22. doi: 10.1007/978-3-662-49651-0_5. Recent Results Cancer Res. 2016. PMID: 27318683 Review.

10

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia.

Ashton TM, Fokas E, Kunz-Schughart LA, Folkes LK, Anbalagan S, Huether M, Kelly CJ, Pirovano G, Buffa FM, Hammond EM, Stratford M, Muschel RJ, Higgins GS, McKenna WG. Ashton TM, et al. Among authors: higgins gs. Nat Commun. 2016 Jul 25;7:12308. doi: 10.1038/ncomms12308. Nat Commun. 2016. PMID: 27453292 Free PMC article.

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