McKenna WG - Search Results

1

TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy.

Pirovano G, Ashton TM, Herbert KJ, Bryant RJ, Verrill CL, Cerundolo L, Buffa FM, Prevo R, Harrap I, Ryan AJ, Macaulay V, McKenna WG, Higgins GS. Pirovano G, et al. Among authors: mckenna wg. Br J Cancer. 2017 Aug 8;117(4):503-512. doi: 10.1038/bjc.2017.197. Epub 2017 Jul 4. Br J Cancer. 2017. PMID: 28677687 Free PMC article.

2

A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.

Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. Higgins GS, et al. Among authors: mckenna wg. Cancer Res. 2010 Apr 1;70(7):2984-93. doi: 10.1158/0008-5472.CAN-09-4040. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233878 Free PMC article.

3

Depletion of signal recognition particle 72kDa increases radiosensitivity.

Prevo R, Tiwana GS, Maughan TS, Buffa FM, McKenna WG, Higgins GS. Prevo R, et al. Among authors: mckenna wg. Cancer Biol Ther. 2017 Jun 3;18(6):425-432. doi: 10.1080/15384047.2017.1323587. Epub 2017 May 11. Cancer Biol Ther. 2017. PMID: 28494188 Free PMC article.

4

CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner.

Prevo R, Pirovano G, Puliyadi R, Herbert KJ, Rodriguez-Berriguete G, O'Docherty A, Greaves W, McKenna WG, Higgins GS. Prevo R, et al. Among authors: mckenna wg. Cell Cycle. 2018;17(12):1513-1523. doi: 10.1080/15384101.2018.1491236. Epub 2018 Jul 25. Cell Cycle. 2018. PMID: 30045664 Free PMC article.

5

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia.

Ashton TM, Fokas E, Kunz-Schughart LA, Folkes LK, Anbalagan S, Huether M, Kelly CJ, Pirovano G, Buffa FM, Hammond EM, Stratford M, Muschel RJ, Higgins GS, McKenna WG. Ashton TM, et al. Among authors: mckenna wg. Nat Commun. 2016 Jul 25;7:12308. doi: 10.1038/ncomms12308. Nat Commun. 2016. PMID: 27453292 Free PMC article.

6

Overexpression of POLQ confers a poor prognosis in early breast cancer patients.

Higgins GS, Harris AL, Prevo R, Helleday T, McKenna WG, Buffa FM. Higgins GS, et al. Among authors: mckenna wg. Oncotarget. 2010 Jul;1(3):175-84. doi: 10.18632/oncotarget.124. Oncotarget. 2010. PMID: 20700469 Free PMC article.

7

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.

Fokas E, Yoshimura M, Prevo R, Higgins G, Hackl W, Maira SM, Bernhard EJ, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: mckenna wg. Radiat Oncol. 2012 Mar 27;7:48. doi: 10.1186/1748-717X-7-48. Radiat Oncol. 2012. PMID: 22452803 Free PMC article.

8

The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.

Prevo R, Fokas E, Reaper PM, Charlton PA, Pollard JR, McKenna WG, Muschel RJ, Brunner TB. Prevo R, et al. Among authors: mckenna wg. Cancer Biol Ther. 2012 Sep;13(11):1072-81. doi: 10.4161/cbt.21093. Epub 2012 Jul 24. Cancer Biol Ther. 2012. PMID: 22825331 Free PMC article.

9

Drug radiotherapy combinations: review of previous failures and reasons for future optimism.

Higgins GS, O'Cathail SM, Muschel RJ, McKenna WG. Higgins GS, et al. Among authors: mckenna wg. Cancer Treat Rev. 2015 Feb;41(2):105-13. doi: 10.1016/j.ctrv.2014.12.012. Epub 2015 Jan 3. Cancer Treat Rev. 2015. PMID: 25579753 Review.

10

Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen.

Tiwana GS, Prevo R, Buffa FM, Yu S, Ebner DV, Howarth A, Folkes LK, Budwal B, Chu KY, Durrant L, Muschel RJ, McKenna WG, Higgins GS. Tiwana GS, et al. Among authors: mckenna wg. Oncotarget. 2015 Mar 20;6(8):5978-89. doi: 10.18632/oncotarget.3468. Oncotarget. 2015. PMID: 25788274 Free PMC article.

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