Chen X - Search Results

1

Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation.

Lan X, Zhao C, Chen X, Zhang P, Zang D, Wu J, Chen J, Long H, Yang L, Huang H, Wang X, Shi X, Liu J. Lan X, et al. Among authors: chen j, chen x. Cell Death Dis. 2017 Jul 6;8(7):e2913. doi: 10.1038/cddis.2017.284. Cell Death Dis. 2017. PMID: 28682311 Free PMC article.

2

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth.

Liu N, Li X, Huang H, Zhao C, Liao S, Yang C, Liu S, Song W, Lu X, Lan X, Chen X, Yi S, Xu L, Jiang L, Zhao C, Dong X, Zhou P, Li S, Wang S, Shi X, Dou PQ, Wang X, Liu J. Liu N, et al. Among authors: chen x. Oncotarget. 2014 Jul 30;5(14):5453-71. doi: 10.18632/oncotarget.2113. Oncotarget. 2014. PMID: 24977961 Free PMC article.

3

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms.

Chen X, Shi X, Zhao C, Li X, Lan X, Liu S, Huang H, Liu N, Liao S, Zang D, Song W, Liu Q, Carter BZ, Dou QP, Wang X, Liu J. Chen X, et al. Oncotarget. 2014 Oct 15;5(19):9118-32. doi: 10.18632/oncotarget.2361. Oncotarget. 2014. PMID: 25193854 Free PMC article.

4

Gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition.

Shi X, Lan X, Chen X, Zhao C, Li X, Liu S, Huang H, Liu N, Zang D, Liao Y, Zhang P, Wang X, Liu J. Shi X, et al. Among authors: chen x. Sci Rep. 2015 Apr 8;5:9694. doi: 10.1038/srep09694. Sci Rep. 2015. PMID: 25853502 Free PMC article.

5

Novel use of old drug: Anti-rheumatic agent auranofin overcomes imatinib-resistance of chronic myeloid leukemia cells.

Chen X, Shi X, Wang X, Liu J. Chen X, et al. Cancer Cell Microenviron. 2014 Nov 1;1(6):e415. doi: 10.14800/ccm.415. Cancer Cell Microenviron. 2014. PMID: 25995993 Free PMC article.

6

Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.

Huang H, Liao Y, Liu N, Hua X, Cai J, Yang C, Long H, Zhao C, Chen X, Lan X, Zang D, Wu J, Li X, Shi X, Wang X, Liu J. Huang H, et al. Among authors: chen x. Oncotarget. 2016 Jan 19;7(3):2796-808. doi: 10.18632/oncotarget.6425. Oncotarget. 2016. PMID: 26625200 Free PMC article.

7

Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy.

Zhao C, Chen X, Zang D, Lan X, Liao S, Yang C, Zhang P, Wu J, Li X, Liu N, Liao Y, Huang H, Shi X, Jiang L, Liu X, He Z, Wang X, Liu J. Zhao C, et al. Among authors: chen x. Biochem Pharmacol. 2016 Sep 15;116:22-38. doi: 10.1016/j.bcp.2016.06.019. Epub 2016 Jul 2. Biochem Pharmacol. 2016. PMID: 27381943 Free PMC article.

8

Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms.

Lan X, Zhao C, Chen X, Zhang P, Zang D, Wu J, Chen J, Long H, Yang L, Huang H, Carter BZ, Wang X, Shi X, Liu J. Lan X, et al. Among authors: chen j, chen x. J Hematol Oncol. 2016 Nov 25;9(1):129. doi: 10.1186/s13045-016-0359-x. J Hematol Oncol. 2016. PMID: 27884201 Free PMC article.

9

Bilirubin neurotoxicity is associated with proteasome inhibition.

Huang H, Guo M, Liu N, Zhao C, Chen H, Wang X, Liao S, Zhou P, Liao Y, Chen X, Lan X, Chen J, Xu D, Li X, Shi X, Yu L, Nie Y, Wang X, Zhang CE, Liu J. Huang H, et al. Among authors: chen j, chen h, chen x. Cell Death Dis. 2017 Jun 15;8(6):e2877. doi: 10.1038/cddis.2017.274. Cell Death Dis. 2017. PMID: 28617443 Free PMC article.

10

Hinokitiol copper complex inhibits proteasomal deubiquitination and induces paraptosis-like cell death in human cancer cells.

Chen X, Zhang X, Chen J, Yang Q, Yang L, Xu D, Zhang P, Wang X, Liu J. Chen X, et al. Among authors: chen j. Eur J Pharmacol. 2017 Nov 15;815:147-155. doi: 10.1016/j.ejphar.2017.09.003. Epub 2017 Sep 5. Eur J Pharmacol. 2017. PMID: 28887042

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