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A randomized, double-blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcerative colitis.
Klughammer B, Piali L, Nica A, Nagel S, Bailey L, Jochum C, Ignatenko S, Bläuer A, Danilin S, Gulati P, Hayward J, Scepanovic P, Zhang JD, Bhosale S, Chong CF, Christ A. Klughammer B, et al. Among authors: ignatenko s. Clin Transl Med. 2023 Nov;13(11):e1471. doi: 10.1002/ctm2.1471. Clin Transl Med. 2023. PMID: 37962000 Free PMC article. Clinical Trial.
Long-acting FC-fusion rhGH (GX-H9) shows potential for up to twice-monthly administration in GH-deficient adults.
Ku CR, Brue T, Schilbach K, Ignatenko S, Magony S, Chung YS, Kim BJ, Hur KY, Kang HC, Kim JH, Kim MS, Kowalska A, Bolanowski M, Ruchala M, Damjanovic S, Payer J, Choi YJ, Heo SJ, Kim TK, Heo M, Lee J, Lee EJ. Ku CR, et al. Among authors: ignatenko s. Eur J Endocrinol. 2018 Sep;179(3):169-179. doi: 10.1530/EJE-18-0185. Epub 2018 Jul 4. Eur J Endocrinol. 2018. PMID: 29973375 Clinical Trial.
Pharmacokinetics of indacaterol, glycopyrronium and mometasone furoate following once-daily inhalation as a combination in healthy subjects.
Vaidya S, Jauernig J, Ethell B, Abdallah N, Machineni S, Drollmann A, Heudi O, Last S, Hahn M, Radhakrishnan R, Ignatenko S, Tillmann HC. Vaidya S, et al. Among authors: ignatenko s. Pulm Pharmacol Ther. 2020 Oct;64:101964. doi: 10.1016/j.pupt.2020.101964. Epub 2020 Oct 6. Pulm Pharmacol Ther. 2020. PMID: 33035700 Free article. Clinical Trial.
Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme.
Krug N, Hohlfeld JM, Kirsten AM, Kornmann O, Beeh KM, Kappeler D, Korn S, Ignatenko S, Timmer W, Rogon C, Zeitvogel J, Zhang N, Bille J, Homburg U, Turowska A, Bachert C, Werfel T, Buhl R, Renz J, Garn H, Renz H. Krug N, et al. Among authors: ignatenko s. N Engl J Med. 2015 May 21;372(21):1987-95. doi: 10.1056/NEJMoa1411776. Epub 2015 May 17. N Engl J Med. 2015. PMID: 25981191 Free article. Clinical Trial.
47 results