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Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids.
McNamara HA, Cai Y, Wagle MV, Sontani Y, Roots CM, Miosge LA, O'Connor JH, Sutton HJ, Ganusov VV, Heath WR, Bertolino P, Goodnow CG, Parish IA, Enders A, Cockburn IA. McNamara HA, et al. Among authors: enders a. Sci Immunol. 2017 Mar;2(9):eaaj1996. doi: 10.1126/sciimmunol.aaj1996. Epub 2017 Mar 17. Sci Immunol. 2017. PMID: 28707003 Free PMC article.
Mouse strains with point mutations in TAP1 and TAP2.
Theodoratos A, Whittle B, Enders A, Tscharke DC, Roots CM, Goodnow CC, Fahrer AM. Theodoratos A, et al. Among authors: enders a. Immunol Cell Biol. 2010 Jan;88(1):72-8. doi: 10.1038/icb.2009.61. Epub 2009 Sep 1. Immunol Cell Biol. 2010. PMID: 19721454
T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow.
Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Roots CM, Beilke JN, Banerjee A, Reiner SL, Miller SA, Weinmann AS, Goodnow CC, Lanier LL, Cyster JG, Chun J. Jenne CN, et al. Among authors: enders a. J Exp Med. 2009 Oct 26;206(11):2469-81. doi: 10.1084/jem.20090525. Epub 2009 Oct 6. J Exp Med. 2009. PMID: 19808259 Free PMC article.
B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.
Bergmann H, Yabas M, Short A, Miosge L, Barthel N, Teh CE, Roots CM, Bull KR, Jeelall Y, Horikawa K, Whittle B, Balakishnan B, Sjollema G, Bertram EM, Mackay F, Rimmer AJ, Cornall RJ, Field MA, Andrews TD, Goodnow CC, Enders A. Bergmann H, et al. Among authors: enders a. J Exp Med. 2013 Jan 14;210(1):31-40. doi: 10.1084/jem.20121076. Epub 2012 Dec 24. J Exp Med. 2013. PMID: 23267016 Free PMC article.
Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.
Bull KR, Rimmer AJ, Siggs OM, Miosge LA, Roots CM, Enders A, Bertram EM, Crockford TL, Whittle B, Potter PK, Simon MM, Mallon AM, Brown SD, Beutler B, Goodnow CC, Lunter G, Cornall RJ. Bull KR, et al. Among authors: enders a. PLoS Genet. 2013;9(1):e1003219. doi: 10.1371/journal.pgen.1003219. Epub 2013 Jan 31. PLoS Genet. 2013. PMID: 23382690 Free PMC article.
Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.
Daley SR, Coakley KM, Hu DY, Randall KL, Jenne CN, Limnander A, Myers DR, Polakos NK, Enders A, Roots C, Balakishnan B, Miosge LA, Sjollema G, Bertram EM, Field MA, Shao Y, Andrews TD, Whittle B, Barnes SW, Walker JR, Cyster JG, Goodnow CC, Roose JP. Daley SR, et al. Among authors: enders a. Elife. 2013 Dec 12;2:e01020. doi: 10.7554/eLife.01020. Elife. 2013. PMID: 24336796 Free PMC article.
Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes.
Enders A, Short A, Miosge LA, Bergmann H, Sontani Y, Bertram EM, Whittle B, Balakishnan B, Yoshida K, Sjollema G, Field MA, Andrews TD, Hagiwara H, Goodnow CC. Enders A, et al. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4513-8. doi: 10.1073/pnas.1402739111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616512 Free PMC article.
Comparison of predicted and actual consequences of missense mutations.
Miosge LA, Field MA, Sontani Y, Cho V, Johnson S, Palkova A, Balakishnan B, Liang R, Zhang Y, Lyon S, Beutler B, Whittle B, Bertram EM, Enders A, Goodnow CC, Andrews TD. Miosge LA, et al. Among authors: enders a. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5189-98. doi: 10.1073/pnas.1511585112. Epub 2015 Aug 12. Proc Natl Acad Sci U S A. 2015. PMID: 26269570 Free PMC article.
389 results