Errey JC - Search Results

1

Structures of Human A₁ and A_2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity.

Cheng RKY, Segala E, Robertson N, Deflorian F, Doré AS, Errey JC, Fiez-Vandal C, Marshall FH, Cooke RM. Cheng RKY, et al. Among authors: errey jc. Structure. 2017 Aug 1;25(8):1275-1285.e4. doi: 10.1016/j.str.2017.06.012. Epub 2017 Jul 14. Structure. 2017. PMID: 28712806 Free article.

2

Biophysical mapping of the adenosine A2A receptor.

Zhukov A, Andrews SP, Errey JC, Robertson N, Tehan B, Mason JS, Marshall FH, Weir M, Congreve M. Zhukov A, et al. Among authors: errey jc. J Med Chem. 2011 Jul 14;54(13):4312-23. doi: 10.1021/jm2003798. Epub 2011 Jun 10. J Med Chem. 2011. PMID: 21661720 Free PMC article.

3

Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine.

Doré AS, Robertson N, Errey JC, Ng I, Hollenstein K, Tehan B, Hurrell E, Bennett K, Congreve M, Magnani F, Tate CG, Weir M, Marshall FH. Doré AS, et al. Among authors: errey jc. Structure. 2011 Sep 7;19(9):1283-93. doi: 10.1016/j.str.2011.06.014. Structure. 2011. PMID: 21885291 Free PMC article.

4

Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A(2A) receptor reconstituted in HDL like particles.

Segala E, Errey JC, Fiez-Vandal C, Zhukov A, Cooke RM. Segala E, et al. Among authors: errey jc. FEBS Lett. 2015 Jun 4;589(13):1399-405. doi: 10.1016/j.febslet.2015.04.030. Epub 2015 Apr 29. FEBS Lett. 2015. PMID: 25935416 Free article.

5

Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.

Segala E, Guo D, Cheng RK, Bortolato A, Deflorian F, Doré AS, Errey JC, Heitman LH, IJzerman AP, Marshall FH, Cooke RM. Segala E, et al. Among authors: errey jc. J Med Chem. 2016 Jul 14;59(13):6470-9. doi: 10.1021/acs.jmedchem.6b00653. Epub 2016 Jul 1. J Med Chem. 2016. PMID: 27312113

6

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A_2A Receptor crystals.

Rucktooa P, Cheng RKY, Segala E, Geng T, Errey JC, Brown GA, Cooke RM, Marshall FH, Doré AS. Rucktooa P, et al. Among authors: errey jc. Sci Rep. 2018 Jan 8;8(1):41. doi: 10.1038/s41598-017-18570-w. Sci Rep. 2018. PMID: 29311713 Free PMC article.

7

Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

Langmead CJ, Andrews SP, Congreve M, Errey JC, Hurrell E, Marshall FH, Mason JS, Richardson CM, Robertson N, Zhukov A, Weir M. Langmead CJ, et al. Among authors: errey jc. J Med Chem. 2012 Mar 8;55(5):1904-9. doi: 10.1021/jm201455y. Epub 2012 Feb 23. J Med Chem. 2012. PMID: 22250781 Free PMC article.

8

Preparation of purified GPCRs for structural studies.

Cooke RM, Koglin M, Errey JC, Marshall FH. Cooke RM, et al. Among authors: errey jc. Biochem Soc Trans. 2013 Feb 1;41(1):185-90. doi: 10.1042/BST20120240. Biochem Soc Trans. 2013. PMID: 23356281

9

Biophysical fragment screening of the β1-adrenergic receptor: identification of high affinity arylpiperazine leads using structure-based drug design.

Christopher JA, Brown J, Doré AS, Errey JC, Koglin M, Marshall FH, Myszka DG, Rich RL, Tate CG, Tehan B, Warne T, Congreve M. Christopher JA, et al. Among authors: errey jc. J Med Chem. 2013 May 9;56(9):3446-55. doi: 10.1021/jm400140q. Epub 2013 Apr 9. J Med Chem. 2013. PMID: 23517028 Free PMC article.

10

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Doré AS, Okrasa K, Patel JC, Serrano-Vega M, Bennett K, Cooke RM, Errey JC, Jazayeri A, Khan S, Tehan B, Weir M, Wiggin GR, Marshall FH. Doré AS, et al. Among authors: errey jc. Nature. 2014 Jul 31;511(7511):557-62. doi: 10.1038/nature13396. Epub 2014 Jul 6. Nature. 2014. PMID: 25042998

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