Matheson CJ - Search Results

1

Selective Targeting of RSK Isoforms in Cancer.

Casalvieri KA, Matheson CJ, Backos DS, Reigan P. Casalvieri KA, et al. Among authors: matheson cj. Trends Cancer. 2017 Apr;3(4):302-312. doi: 10.1016/j.trecan.2017.03.004. Epub 2017 Apr 3. Trends Cancer. 2017. PMID: 28718440 Review.

2

Strategies and Approaches of Targeting STAT3 for Cancer Treatment.

Furtek SL, Backos DS, Matheson CJ, Reigan P. Furtek SL, et al. Among authors: matheson cj. ACS Chem Biol. 2016 Feb 19;11(2):308-18. doi: 10.1021/acschembio.5b00945. Epub 2016 Jan 15. ACS Chem Biol. 2016. PMID: 26730496 Review.

3

Targeting WEE1 Kinase in Cancer.

Matheson CJ, Backos DS, Reigan P. Matheson CJ, et al. Trends Pharmacol Sci. 2016 Oct;37(10):872-881. doi: 10.1016/j.tips.2016.06.006. Epub 2016 Jul 14. Trends Pharmacol Sci. 2016. PMID: 27427153 Review.

4

Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study.

Casalvieri KA, Matheson CJ, Backos DS, Reigan P. Casalvieri KA, et al. Among authors: matheson cj. Bioorg Med Chem. 2020 Mar 1;28(5):115303. doi: 10.1016/j.bmc.2019.115303. Epub 2020 Jan 12. Bioorg Med Chem. 2020. PMID: 31982240

5

N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors.

Casalvieri KA, Matheson CJ, Warfield BM, Backos DS, Reigan P. Casalvieri KA, et al. Among authors: matheson cj. Bioorg Med Chem. 2021 Jul 1;41:116220. doi: 10.1016/j.bmc.2021.116220. Epub 2021 May 19. Bioorg Med Chem. 2021. PMID: 34034149

6

RSK3: A regulator of pathological cardiac remodeling.

Martinez EC, Passariello CL, Li J, Matheson CJ, Dodge-Kafka K, Reigan P, Kapiloff MS. Martinez EC, et al. Among authors: matheson cj. IUBMB Life. 2015 May;67(5):331-7. doi: 10.1002/iub.1383. Epub 2015 May 19. IUBMB Life. 2015. PMID: 25988524 Free PMC article. Review.

7

Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary Tumors.

Xiong W, Matheson CJ, Xu M, Backos DS, Mills TS, Salian-Mehta S, Kiseljak-Vassiliades K, Reigan P, Wierman ME. Xiong W, et al. Among authors: matheson cj. Mol Cancer Ther. 2016 Mar;15(3):412-20. doi: 10.1158/1535-7163.MCT-15-0703. Epub 2015 Dec 31. Mol Cancer Ther. 2016. PMID: 26721946 Free PMC article.

8

A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.

Matheson CJ, Venkataraman S, Amani V, Harris PS, Backos DS, Donson AM, Wempe MF, Foreman NK, Vibhakar R, Reigan P. Matheson CJ, et al. ACS Chem Biol. 2016 Apr 15;11(4):921-30. doi: 10.1021/acschembio.5b00725. Epub 2016 Jan 8. ACS Chem Biol. 2016. PMID: 26745241

9

Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors.

Furtek SL, Matheson CJ, Backos DS, Reigan P. Furtek SL, et al. Among authors: matheson cj. Oncotarget. 2016 Nov 22;7(47):77998-78008. doi: 10.18632/oncotarget.12868. Oncotarget. 2016. PMID: 27793003 Free PMC article.

10

Development of Potent Pyrazolopyrimidinone-Based WEE1 Inhibitors with Limited Single-Agent Cytotoxicity for Cancer Therapy.

Matheson CJ, Casalvieri KA, Backos DS, Reigan P. Matheson CJ, et al. ChemMedChem. 2018 Aug 20;13(16):1681-1694. doi: 10.1002/cmdc.201800188. Epub 2018 Jul 11. ChemMedChem. 2018. PMID: 29883531 Free PMC article.

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