Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes.
Deng N, Wu YY, Feng Y, Hsieh WC, Song JS, Lin YS, Tseng YH, Liao WJ, Chu YF, Liu YC, Chang EC, Liu CR, Sheu SY, Su MT, Kuo HC, Cohen SN, Cheng TH.
Deng N, et al. Among authors: liu yc, liu cr.
Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204779119. doi: 10.1073/pnas.2204779119. Epub 2022 Aug 1.
Proc Natl Acad Sci U S A. 2022.
PMID: 35914128
Free PMC article.