Wu X - Search Results

1

Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies.

Froning KJ, Leaver-Fay A, Wu X, Phan S, Gao L, Huang F, Pustilnik A, Bacica M, Houlihan K, Chai Q, Fitchett JR, Hendle J, Kuhlman B, Demarest SJ. Froning KJ, et al. Among authors: wu x. Protein Sci. 2017 Oct;26(10):2021-2038. doi: 10.1002/pro.3240. Epub 2017 Jul 31. Protein Sci. 2017. PMID: 28726352 Free PMC article.

2

Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.

Lewis SM, Wu X, Pustilnik A, Sereno A, Huang F, Rick HL, Guntas G, Leaver-Fay A, Smith EM, Ho C, Hansen-Estruch C, Chamberlain AK, Truhlar SM, Conner EM, Atwell S, Kuhlman B, Demarest SJ. Lewis SM, et al. Among authors: wu x. Nat Biotechnol. 2014 Feb;32(2):191-8. doi: 10.1038/nbt.2797. Epub 2014 Jan 26. Nat Biotechnol. 2014. PMID: 24463572

3

Protein design of IgG/TCR chimeras for the co-expression of Fab-like moieties within bispecific antibodies.

Wu X, Sereno AJ, Huang F, Zhang K, Batt M, Fitchett JR, He D, Rick HL, Conner EM, Demarest SJ. Wu X, et al. MAbs. 2015;7(2):364-76. doi: 10.1080/19420862.2015.1007826. MAbs. 2015. PMID: 25611120 Free PMC article.

4

Fab-based bispecific antibody formats with robust biophysical properties and biological activity.

Wu X, Sereno AJ, Huang F, Lewis SM, Lieu RL, Weldon C, Torres C, Fine C, Batt MA, Fitchett JR, Glasebrook AL, Kuhlman B, Demarest SJ. Wu X, et al. MAbs. 2015;7(3):470-82. doi: 10.1080/19420862.2015.1022694. MAbs. 2015. PMID: 25774965 Free PMC article.

5

Transient and stable CHO expression, purification and characterization of novel hetero-dimeric bispecific IgG antibodies.

Rajendra Y, Peery RB, Hougland MD, Barnard GC, Wu X, Fitchett JR, Bacica M, Demarest SJ. Rajendra Y, et al. Among authors: wu x. Biotechnol Prog. 2017 Mar;33(2):469-477. doi: 10.1002/btpr.2414. Epub 2017 Feb 3. Biotechnol Prog. 2017. PMID: 27977915

6

Generation of orthogonal Fab-based trispecific antibody formats.

Wu X, Yuan R, Bacica M, Demarest SJ. Wu X, et al. Protein Eng Des Sel. 2018 Jul 1;31(7-8):249-256. doi: 10.1093/protein/gzy007. Protein Eng Des Sel. 2018. PMID: 29718394

7

Building blocks for bispecific and trispecific antibodies.

Wu X, Demarest SJ. Wu X, et al. Methods. 2019 Feb 1;154:3-9. doi: 10.1016/j.ymeth.2018.08.010. Epub 2018 Aug 30. Methods. 2019. PMID: 30172007 Review.

8

Comparing domain interactions within antibody Fabs with kappa and lambda light chains.

Toughiri R, Wu X, Ruiz D, Huang F, Crissman JW, Dickey M, Froning K, Conner EM, Cujec TP, Demarest SJ. Toughiri R, et al. Among authors: wu x. MAbs. 2016 Oct;8(7):1276-1285. doi: 10.1080/19420862.2016.1214785. Epub 2016 Jul 25. MAbs. 2016. PMID: 27454112 Free PMC article.

9

Glycosylation Profiling of α/β T Cell Receptor Constant Domains Expressed in Mammalian Cells.

Zhang K, Demarest SJ, Wu X, Fitchett JR. Zhang K, et al. Among authors: wu x. Methods Mol Biol. 2017;1575:197-213. doi: 10.1007/978-1-4939-6857-2_12. Methods Mol Biol. 2017. PMID: 28255882

10

Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.

Froning K, Maguire J, Sereno A, Huang F, Chang S, Weichert K, Frommelt AJ, Dong J, Wu X, Austin H, Conner EM, Fitchett JR, Heng AR, Balasubramaniam D, Hilgers MT, Kuhlman B, Demarest SJ. Froning K, et al. Among authors: wu x. Nat Commun. 2020 May 11;11(1):2330. doi: 10.1038/s41467-020-16231-7. Nat Commun. 2020. PMID: 32393818 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

59,230 results

Search Page

Filters