Delahaye S - Search Results

1

The metabolism and drug-drug interaction potential of the selective prostacyclin receptor agonist selexipag.

Gnerre C, Segrestaa J, Seeland S, Äänismaa P, Pfeifer T, Delahaye S, de Kanter R, Ichikawa T, Yamada T, Treiber A. Gnerre C, et al. Among authors: delahaye s. Xenobiotica. 2018 Jul;48(7):704-719. doi: 10.1080/00498254.2017.1357088. Epub 2017 Aug 30. Xenobiotica. 2018. PMID: 28737453 Clinical Trial.

2

Inhibition of organic anion transporting polypeptide-mediated hepatic uptake is the major determinant in the pharmacokinetic interaction between bosentan and cyclosporin A in the rat.

Treiber A, Schneiter R, Delahaye S, Clozel M. Treiber A, et al. Among authors: delahaye s. J Pharmacol Exp Ther. 2004 Mar;308(3):1121-9. doi: 10.1124/jpet.103.061614. Epub 2003 Nov 14. J Pharmacol Exp Ther. 2004. PMID: 14617681

3

Design and preparation of potent, nonpeptidic, bioavailable renin inhibitors.

Bezençon O, Bur D, Weller T, Richard-Bildstein S, Remen L, Sifferlen T, Corminboeuf O, Grisostomi C, Boss C, Prade L, Delahaye S, Treiber A, Strickner P, Binkert C, Hess P, Steiner B, Fischli W. Bezençon O, et al. Among authors: delahaye s. J Med Chem. 2009 Jun 25;52(12):3689-702. doi: 10.1021/jm900022f. J Med Chem. 2009. PMID: 19358611

4

New classes of potent and bioavailable human renin inhibitors.

Remen L, Bezençon O, Richard-Bildstein S, Bur D, Prade L, Corminboeuf O, Boss C, Grisostomi C, Sifferlen T, Strickner P, Hess P, Delahaye S, Treiber A, Weller T, Binkert C, Steiner B, Fischli W. Remen L, et al. Among authors: delahaye s. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6762-5. doi: 10.1016/j.bmcl.2009.09.104. Epub 2009 Oct 1. Bioorg Med Chem Lett. 2009. PMID: 19853442

5

Macitentan does not interfere with hepatic bile salt transport.

Treiber A, Äänismaa P, de Kanter R, Delahaye S, Treher M, Hess P, Sidharta P. Treiber A, et al. Among authors: delahaye s. J Pharmacol Exp Ther. 2014 Jul;350(1):130-43. doi: 10.1124/jpet.114.214106. Epub 2014 Apr 25. J Pharmacol Exp Ther. 2014. PMID: 24769543 Free article. Clinical Trial.

6

Physiologically-Based Pharmacokinetic Modeling of Macitentan: Prediction of Drug-Drug Interactions.

de Kanter R, Sidharta PN, Delahaye S, Gnerre C, Segrestaa J, Buchmann S, Kohl C, Treiber A. de Kanter R, et al. Among authors: delahaye s. Clin Pharmacokinet. 2016 Mar;55(3):369-80. doi: 10.1007/s40262-015-0322-y. Clin Pharmacokinet. 2016. PMID: 26385839

7

The endothelin receptor antagonist macitentan for the treatment of pulmonary arterial hypertension: A cross-species comparison of its cytochrome P450 induction pattern.

Treiber A, Delahaye S, Seeland S, Gnerre C. Treiber A, et al. Among authors: delahaye s. Pharmacol Res Perspect. 2020 Aug;8(4):e00619. doi: 10.1002/prp2.619. Pharmacol Res Perspect. 2020. PMID: 32613761 Free PMC article.

8

The metabolism of the dual orexin receptor antagonist daridorexant.

Treiber A, Delahaye S, Weigel A, Aeänismaa P, Gatfield J, Seeland S. Treiber A, et al. Among authors: delahaye s. Xenobiotica. 2023 Mar;53(3):173-183. doi: 10.1080/00498254.2023.2183159. Epub 2023 May 11. Xenobiotica. 2023. PMID: 36809238

9

CYP3A4 Catalyzes the Rearrangement of the Dual Orexin Receptor Antagonist Daridorexant to 4-Hydroxypiperidinol Metabolites.

Treiber A, Aissaoui H, Delahaye S, Glutz S, Grimont J, Müller C, Seeland S, Siefken V, Boss C. Treiber A, et al. Among authors: delahaye s. ChemMedChem. 2023 May 16;18(10):e202300030. doi: 10.1002/cmdc.202300030. Epub 2023 Apr 12. ChemMedChem. 2023. PMID: 36892179

10

No influence of the endothelin receptor antagonist bosentan on basal and indomethacin-induced reduction of cerebral blood flow in pigs.

Rasmussen M, Poulsen PH, Treiber A, Delahaye S, Tankisi A, Cold GE, Therkelsen K, Gjedde A, Astrup J. Rasmussen M, et al. Among authors: delahaye s. Acta Anaesthesiol Scand. 2003 Feb;47(2):200-7. doi: 10.1034/j.1399-6576.2003.00019.x. Acta Anaesthesiol Scand. 2003. PMID: 12631050

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