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PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.
Mzoughi S, Zhang J, Hequet D, Teo SX, Fang H, Xing QR, Bezzi M, Seah MKY, Ong SLM, Shin EM, Wollmann H, Wong ESM, Al-Haddawi M, Stewart CL, Tergaonkar V, Loh YH, Dunn NR, Messerschmidt DM, Guccione E. Mzoughi S, et al. Among authors: messerschmidt dm. Nat Genet. 2017 Sep;49(9):1354-1363. doi: 10.1038/ng.3922. Epub 2017 Jul 24. Nat Genet. 2017. PMID: 28740264
A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo.
Do DV, Ueda J, Messerschmidt DM, Lorthongpanich C, Zhou Y, Feng B, Guo G, Lin PJ, Hossain MZ, Zhang W, Moh A, Wu Q, Robson P, Ng HH, Poellinger L, Knowles BB, Solter D, Fu XY. Do DV, et al. Among authors: messerschmidt dm. Genes Dev. 2013 Jun 15;27(12):1378-90. doi: 10.1101/gad.221176.113. Genes Dev. 2013. PMID: 23788624 Free PMC article.
Loss of maternal Trim28 causes male-predominant early embryonic lethality.
Sampath Kumar A, Seah MK, Ling KY, Wang Y, Tan JH, Nitsch S, Lim SL, Lorthongpanich C, Wollmann H, Low DH, Guccione E, Messerschmidt DM. Sampath Kumar A, et al. Among authors: messerschmidt dm. Genes Dev. 2017 Jan 1;31(1):12-17. doi: 10.1101/gad.291195.116. Epub 2017 Jan 23. Genes Dev. 2017. PMID: 28115466 Free PMC article.
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice.
Ho L, van Dijk M, Chye STJ, Messerschmidt DM, Chng SC, Ong S, Yi LK, Boussata S, Goh GH, Afink GB, Lim CY, Dunn NR, Solter D, Knowles BB, Reversade B. Ho L, et al. Among authors: messerschmidt dm. Science. 2017 Aug 18;357(6352):707-713. doi: 10.1126/science.aam6607. Epub 2017 Jun 29. Science. 2017. PMID: 28663440
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I.
Palmer N, Talib SZA, Ratnacaram CK, Low D, Bisteau X, Lee JHS, Pfeiffenberger E, Wollmann H, Tan JHL, Wee S, Sobota R, Gunaratne J, Messerschmidt DM, Guccione E, Kaldis P. Palmer N, et al. Among authors: messerschmidt dm. J Cell Biol. 2019 Sep 2;218(9):2896-2918. doi: 10.1083/jcb.201903125. Epub 2019 Jul 26. J Cell Biol. 2019. PMID: 31350280 Free PMC article.
27 results