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Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)A Receptor.
Martinez Botella G, Salituro FG, Harrison BL, Beresis RT, Bai Z, Blanco MJ, Belfort GM, Dai J, Loya CM, Ackley MA, Althaus AL, Grossman SJ, Hoffmann E, Doherty JJ, Robichaud AJ. Martinez Botella G, et al. Among authors: bai z. J Med Chem. 2017 Sep 28;60(18):7810-7819. doi: 10.1021/acs.jmedchem.7b00846. Epub 2017 Aug 17. J Med Chem. 2017. PMID: 28753313
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21.
Martinez Botella G, Salituro FG, Harrison BL, Beresis RT, Bai Z, Shen K, Belfort GM, Loya CM, Ackley MA, Grossman SJ, Hoffmann E, Jia S, Wang J, Doherty JJ, Robichaud AJ. Martinez Botella G, et al. Among authors: bai z. J Med Chem. 2015 Apr 23;58(8):3500-11. doi: 10.1021/acs.jmedchem.5b00032. Epub 2015 Apr 14. J Med Chem. 2015. PMID: 25799373
SAGE-718: A First-in-Class N-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment.
Hill MD, Blanco MJ, Salituro FG, Bai Z, Beckley JT, Ackley MA, Dai J, Doherty JJ, Harrison BL, Hoffmann EC, Kazdoba TM, Lanzetta D, Lewis M, Quirk MC, Robichaud AJ. Hill MD, et al. Among authors: bai z. J Med Chem. 2022 Jul 14;65(13):9063-9075. doi: 10.1021/acs.jmedchem.2c00313. Epub 2022 Jul 2. J Med Chem. 2022. PMID: 35785990
Observed Effects on Very Early Pregnancy Linked to Ambient PM2.5 Exposure in China among Women Undergoing In Vitro Fertilization-Embryo Transfer.
Lan C, Guan Y, Luo H, Ma X, Yang Y, Bao H, Hao C, He X, Zhang H, Gao N, Lin W, Ren M, Wu T, Wang C, Ni X, Shen C, Zhang J, Ma J, Zhang R, Bi Y, Zhuang L, Miao R, Song Z, An T, Liu Z, Pan B, Fang M, Liu J, Bai Z, Meng F, Chen Y, Lu X, Guo Y, Cao Y, Lu Q, Wang B. Lan C, et al. Among authors: bai z. Environ Health (Wash). 2024 Oct 21;2(12):918-928. doi: 10.1021/envhealth.4c00107. eCollection 2024 Dec 20. Environ Health (Wash). 2024. PMID: 39722841 Free PMC article.
3,449 results