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Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media.
Fukuta M, Nakai Y, Kirino K, Nakagawa M, Sekiguchi K, Nagata S, Matsumoto Y, Yamamoto T, Umeda K, Heike T, Okumura N, Koizumi N, Sato T, Nakahata T, Saito M, Otsuka T, Kinoshita S, Ueno M, Ikeya M, Toguchida J. Fukuta M, et al. Among authors: nagata s. PLoS One. 2014 Dec 2;9(12):e112291. doi: 10.1371/journal.pone.0112291. eCollection 2014. PLoS One. 2014. PMID: 25464501 Free PMC article.
Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.
Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T Jr, Okamoto T, Matsuda S, Toguchida J. Jin Y, et al. Among authors: nagata s. PLoS One. 2015 Jul 10;10(7):e0131998. doi: 10.1371/journal.pone.0131998. eCollection 2015. PLoS One. 2015. PMID: 26161668 Free PMC article.
Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.
Hino K, Ikeya M, Horigome K, Matsumoto Y, Ebise H, Nishio M, Sekiguchi K, Shibata M, Nagata S, Matsuda S, Toguchida J. Hino K, et al. Among authors: nagata s. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15438-43. doi: 10.1073/pnas.1510540112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2015. PMID: 26621707 Free PMC article.
In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes.
Kawai S, Yoshitomi H, Sunaga J, Alev C, Nagata S, Nishio M, Hada M, Koyama Y, Uemura M, Sekiguchi K, Maekawa H, Ikeya M, Tamaki S, Jin Y, Harada Y, Fukiage K, Adachi T, Matsuda S, Toguchida J. Kawai S, et al. Among authors: nagata s. Nat Biomed Eng. 2019 Jul;3(7):558-570. doi: 10.1038/s41551-019-0410-7. Epub 2019 Jun 10. Nat Biomed Eng. 2019. PMID: 31182836
2,147 results