Wulff H - Search Results

1

Structural Determinants for the Selectivity of the Positive KCa3.1 Gating Modulator 5-Methylnaphtho[2,1-d]oxazol-2-amine (SKA-121).

Brown BM, Shim H, Zhang M, Yarov-Yarovoy V, Wulff H. Brown BM, et al. Among authors: wulff h. Mol Pharmacol. 2017 Oct;92(4):469-480. doi: 10.1124/mol.117.109421. Epub 2017 Jul 31. Mol Pharmacol. 2017. PMID: 28760780 Free PMC article.

2

Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.

Vennekamp J, Wulff H, Beeton C, Calabresi PA, Grissmer S, Hänsel W, Chandy KG. Vennekamp J, et al. Among authors: wulff h. Mol Pharmacol. 2004 Jun;65(6):1364-74. doi: 10.1124/mol.65.6.1364. Mol Pharmacol. 2004. PMID: 15155830

3

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases.

Beeton C, Pennington MW, Wulff H, Singh S, Nugent D, Crossley G, Khaytin I, Calabresi PA, Chen CY, Gutman GA, Chandy KG. Beeton C, et al. Among authors: wulff h. Mol Pharmacol. 2005 Apr;67(4):1369-81. doi: 10.1124/mol.104.008193. Epub 2005 Jan 21. Mol Pharmacol. 2005. PMID: 15665253 Free PMC article.

4

Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases.

Schmitz A, Sankaranarayanan A, Azam P, Schmidt-Lassen K, Homerick D, Hänsel W, Wulff H. Schmitz A, et al. Among authors: wulff h. Mol Pharmacol. 2005 Nov;68(5):1254-70. doi: 10.1124/mol.105.015669. Epub 2005 Aug 11. Mol Pharmacol. 2005. PMID: 16099841

5

Modulators of small- and intermediate-conductance calcium-activated potassium channels and their therapeutic indications.

Wulff H, Kolski-Andreaco A, Sankaranarayanan A, Sabatier JM, Shakkottai V. Wulff H, et al. Curr Med Chem. 2007;14(13):1437-57. doi: 10.2174/092986707780831186. Curr Med Chem. 2007. PMID: 17584055 Review.

6

Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure.

Sankaranarayanan A, Raman G, Busch C, Schultz T, Zimin PI, Hoyer J, Köhler R, Wulff H. Sankaranarayanan A, et al. Among authors: wulff h. Mol Pharmacol. 2009 Feb;75(2):281-95. doi: 10.1124/mol.108.051425. Epub 2008 Oct 27. Mol Pharmacol. 2009. PMID: 18955585 Free PMC article.

7

Potassium channel block by a tripartite complex of two cationophilic ligands and a potassium ion.

Zimin PI, Garic B, Bodendiek SB, Mahieux C, Wulff H, Zhorov BS. Zimin PI, et al. Among authors: wulff h. Mol Pharmacol. 2010 Oct;78(4):588-99. doi: 10.1124/mol.110.064014. Epub 2010 Jul 2. Mol Pharmacol. 2010. PMID: 20601455 Free PMC article.

8

Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels.

Jenkins DP, Strøbæk D, Hougaard C, Jensen ML, Hummel R, Sørensen US, Christophersen P, Wulff H. Jenkins DP, et al. Among authors: wulff h. Mol Pharmacol. 2011 Jun;79(6):899-909. doi: 10.1124/mol.110.069807. Epub 2011 Mar 1. Mol Pharmacol. 2011. PMID: 21363929 Free PMC article.

9

Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets.

Wulff H, Köhler R. Wulff H, et al. J Cardiovasc Pharmacol. 2013 Feb;61(2):102-12. doi: 10.1097/FJC.0b013e318279ba20. J Cardiovasc Pharmacol. 2013. PMID: 23107876 Free PMC article. Review.

10

Channels: Sticking to nooks and crannies.

Wulff H, Yarov-Yarovoy V. Wulff H, et al. Nat Chem Biol. 2013 Aug;9(8):473-4. doi: 10.1038/nchembio.1292. Nat Chem Biol. 2013. PMID: 23868316

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