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Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors.
Tan C, de Noronha RG, Devi NS, Jabbar AA, Kaluz S, Liu Y, Mooring SR, Nicolaou KC, Wang B, Van Meir EG. Tan C, et al. Among authors: kaluz s. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5528-32. doi: 10.1016/j.bmcl.2011.06.099. Epub 2011 Jun 28. Bioorg Med Chem Lett. 2011. PMID: 21831638 Free PMC article.
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.
Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, Zhang Z, Boreddy PR, Wang W, Wang Z, Abbruscato T, Chen Z, Olson JJ, Zhang R, Goodman MM, Nicolaou KC, Van Meir EG. Yin S, et al. Among authors: kaluz s. Clin Cancer Res. 2012 Dec 15;18(24):6623-33. doi: 10.1158/1078-0432.CCR-12-0861. Epub 2012 Aug 24. Clin Cancer Res. 2012. PMID: 22923450 Free PMC article.
Taking a HIF pill for old age diseases?
Kaluz S, Tan C, Van Meir EG. Kaluz S, et al. Aging (Albany NY). 2018 Mar 1;10(3):290-292. doi: 10.18632/aging.101395. Aging (Albany NY). 2018. PMID: 29500331 Free PMC article. No abstract available.
78 results