St-Germain J - Search Results

1

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

Kim BR, Coyaud E, Laurent EMN, St-Germain J, Van de Laar E, Tsao MS, Raught B, Moghal N. Kim BR, et al. Mol Cell Proteomics. 2017 Oct;16(10):1864-1888. doi: 10.1074/mcp.M116.064451. Epub 2017 Aug 9. Mol Cell Proteomics. 2017. PMID: 28794006 Free PMC article.

2

Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.

Organ SL, Tong J, Taylor P, St-Germain JR, Navab R, Moran MF, Tsao MS. Organ SL, et al. J Proteome Res. 2011 Jul 1;10(7):3200-11. doi: 10.1021/pr200238t. Epub 2011 Jun 9. J Proteome Res. 2011. PMID: 21609022

3

Global Interactomics Uncovers Extensive Organellar Targeting by Zika Virus.

Coyaud E, Ranadheera C, Cheng D, Gonçalves J, Dyakov BJA, Laurent EMN, St-Germain J, Pelletier L, Gingras AC, Brumell JH, Kim PK, Safronetz D, Raught B. Coyaud E, et al. Mol Cell Proteomics. 2018 Nov;17(11):2242-2255. doi: 10.1074/mcp.TIR118.000800. Epub 2018 Jul 23. Mol Cell Proteomics. 2018. PMID: 30037810 Free PMC article.

4

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation.

Kano Y, Gebregiworgis T, Marshall CB, Radulovich N, Poon BPK, St-Germain J, Cook JD, Valencia-Sama I, Grant BMM, Herrera SG, Miao J, Raught B, Irwin MS, Lee JE, Yeh JJ, Zhang ZY, Tsao MS, Ikura M, Ohh M. Kano Y, et al. Nat Commun. 2019 Jan 15;10(1):224. doi: 10.1038/s41467-018-08115-8. Nat Commun. 2019. PMID: 30644389 Free PMC article.

5

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.

Ishizawa J, Zarabi SF, Davis RE, Halgas O, Nii T, Jitkova Y, Zhao R, St-Germain J, Heese LE, Egan G, Ruvolo VR, Barghout SH, Nishida Y, Hurren R, Ma W, Gronda M, Link T, Wong K, Mabanglo M, Kojima K, Borthakur G, MacLean N, Ma MCJ, Leber AB, Minden MD, Houry W, Kantarjian H, Stogniew M, Raught B, Pai EF, Schimmer AD, Andreeff M. Ishizawa J, et al. Cancer Cell. 2019 May 13;35(5):721-737.e9. doi: 10.1016/j.ccell.2019.03.014. Epub 2019 May 2. Cancer Cell. 2019. PMID: 31056398 Free PMC article.

6

BioID screen of Salmonella type 3 secreted effectors reveals host factors involved in vacuole positioning and stability during infection.

D'Costa VM, Coyaud E, Boddy KC, Laurent EMN, St-Germain J, Li T, Grinstein S, Raught B, Brumell JH. D'Costa VM, et al. Nat Microbiol. 2019 Dec;4(12):2511-2522. doi: 10.1038/s41564-019-0580-9. Epub 2019 Oct 14. Nat Microbiol. 2019. PMID: 31611645

7

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

Botham A, Coyaud E, Nirmalanandhan VS, Gronda M, Hurren R, Maclean N, St-Germain J, Mirali S, Laurent E, Raught B, Schimmer A. Botham A, et al. Proteomics. 2019 Dec;19(24):e1900139. doi: 10.1002/pmic.201900139. Proteomics. 2019. PMID: 31617661

8

The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.

Mirali S, Botham A, Voisin V, Xu C, St-Germain J, Sharon D, Hoff FW, Qiu Y, Hurren R, Gronda M, Jitkova Y, Nachmias B, MacLean N, Wang X, Arruda A, Minden MD, Horton TM, Kornblau SM, Chan SM, Bader GD, Raught B, Schimmer AD. Mirali S, et al. Sci Transl Med. 2020 Apr 8;12(538):eaaz8264. doi: 10.1126/scitranslmed.aaz8264. Sci Transl Med. 2020. PMID: 32269163

9

The long form of pVHL is artifactually modified by serine protease inhibitor AEBSF.

Tarade D, He S, St-Germain J, Petroff A, Murphy A, Raught B, Ohh M. Tarade D, et al. Protein Sci. 2020 Aug;29(8):1843-1850. doi: 10.1002/pro.3898. Epub 2020 Jun 25. Protein Sci. 2020. PMID: 32535973 Free PMC article.

10

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

St-Germain JR, Samavarchi Tehrani P, Wong C, Larsen B, Gingras AC, Raught B. St-Germain JR, et al. J Proteome Res. 2020 Aug 7;19(8):3554-3561. doi: 10.1021/acs.jproteome.0c00117. Epub 2020 Jul 20. J Proteome Res. 2020. PMID: 32628020

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