Leão RAC - Search Results

1

Studies on the dynamic resolution of Crizotinib intermediate.

de França ADS, Silva MVM, Neves RV, de Souza SP, Leão RAC, Monteiro CM, Rocha Â, Afonso CAM, de Souza ROMA. de França ADS, et al. Among authors: leao rac. Bioorg Med Chem. 2018 Apr 1;26(7):1333-1337. doi: 10.1016/j.bmc.2017.07.024. Epub 2017 Jul 21. Bioorg Med Chem. 2018. PMID: 28802669

2

Continuous-flow protocol for the synthesis of enantiomerically pure intermediates of anti epilepsy and anti tuberculosis active pharmaceutical ingredients.

Aguiar RM, Leão RAC, Mata A, Cantillo D, Kappe CO, Miranda LSM, de Souza ROMA. Aguiar RM, et al. Among authors: leao rac. Org Biomol Chem. 2019 Feb 6;17(6):1552-1557. doi: 10.1039/c8ob03088j. Org Biomol Chem. 2019. PMID: 30693360

3

Cannabidiol Discovery and Synthesis-a Target-Oriented Analysis in Drug Production Processes.

Aguillón AR, Leão RAC, Miranda LSM, de Souza ROMA. Aguillón AR, et al. Among authors: leao rac. Chemistry. 2021 Mar 26;27(18):5577-5600. doi: 10.1002/chem.202002887. Epub 2021 Jan 31. Chemistry. 2021. PMID: 32780909 Review.

4

Lipase-catalyzed acylation of levoglucosan in continuous flow: antibacterial and biosurfactant studies.

do Nascimento MA, Vargas JPC, Rodrigues JGA, Leão RAC, de Moura PHB, Leal ICR, Bassut J, de Souza ROMA, Wojcieszak R, Itabaiana I Jr. do Nascimento MA, et al. Among authors: leao rac. RSC Adv. 2022 Jan 21;12(5):3027-3035. doi: 10.1039/d1ra08111j. eCollection 2022 Jan 18. RSC Adv. 2022. PMID: 35425309 Free PMC article.

5

Continuous-flow synthesis of dimethyl fumarate: a powerful small molecule for the treatment of psoriasis and multiple sclerosis.

Lima MT, Finelli FG, de Oliveira AVB, Kartnaller V, Cajaiba JF, Leão RAC, de Souza ROMA. Lima MT, et al. Among authors: leao rac. RSC Adv. 2020 Jan 16;10(5):2490-2494. doi: 10.1039/c9ra09119j. eCollection 2020 Jan 14. RSC Adv. 2020. PMID: 35496077 Free PMC article.

6

Continuous Flow Synthesis of Hexyl Laurate Using Immobilized Thermomyces Lanuginosus Lipase from Residual Babassu Mesocarp.

de S Lira RK, do Nascimento MA, Lima MT, Georgii ADNP, Leão RAC, de Souza ROMA, Wojcieszak R, Leite SGF, Ivaldo IJ. de S Lira RK, et al. Among authors: leao rac. Chempluschem. 2024 Dec;89(12):e202400442. doi: 10.1002/cplu.202400442. Epub 2024 Oct 8. Chempluschem. 2024. PMID: 39105675

7

Levoglucosenone as a starting material for cascade continuous-flow synthesis of (R)-γ-carboxy-γ-butyrolactone.

Pacheco CM, Lima W, Lima FA, Gomez MRBP, da Silva IG, Miranda LSM, Esteves PM, Itabaiana I Jr, Wojcieszak R, Leão RAC, de Souza ROMA. Pacheco CM, et al. Among authors: leao rac. RSC Adv. 2024 Oct 29;14(47):34611-34619. doi: 10.1039/d4ra06403h. eCollection 2024 Oct 29. RSC Adv. 2024. PMID: 39479490 Free PMC article.

8

New Palladacycle-Derived Acylhydrazones as Pre-catalysts in Mirozoki-Heck Coupling and Oxyarylations.

Leão RAC, Pinho VD, Coelho AS, Kümmerle AE, Costa PRR. Leão RAC, et al. An Acad Bras Cienc. 2018 May 14;90(1 Suppl 2):1273-1278. doi: 10.1590/0001-3765201820170858. Print 2018. An Acad Bras Cienc. 2018. PMID: 29768577 Free article.

9

Theoretical studies and NMR assay of coumarins and neoflavanones derivatives as potential inhibitors of acetylcholinesterase.

de Souza LG, Moraes PF, Leão RAC, Costa PRR, Soares RO, Pascutti PG, Figueroa-Villar JD, Rennó MN. de Souza LG, et al. Among authors: leao rac. Comput Biol Chem. 2020 May 29;87:107293. doi: 10.1016/j.compbiolchem.2020.107293. Online ahead of print. Comput Biol Chem. 2020. PMID: 32559640

10

Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitors.

Nichols DB, Leão RA, Basu A, Chudayeu M, de Moraes Pde F, Talele TT, Costa PR, Kaushik-Basu N. Nichols DB, et al. Chem Biol Drug Des. 2013 May;81(5):607-14. doi: 10.1111/cbdd.12105. Epub 2013 Apr 4. Chem Biol Drug Des. 2013. PMID: 23311976

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