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Page 1
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.
Sadiku P, Willson JA, Dickinson RS, Murphy F, Harris AJ, Lewis A, Sammut D, Mirchandani AS, Ryan E, Watts ER, Thompson AAR, Marriott HM, Dockrell DH, Taylor CT, Schneider M, Maxwell PH, Chilvers ER, Mazzone M, Moral V, Pugh CW, Ratcliffe PJ, Schofield CJ, Ghesquiere B, Carmeliet P, Whyte MK, Walmsley SR. Sadiku P, et al. Among authors: thompson aar. J Clin Invest. 2017 Sep 1;127(9):3407-3420. doi: 10.1172/JCI90848. Epub 2017 Aug 14. J Clin Invest. 2017. PMID: 28805660 Free PMC article.
Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.
Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, Dockrell DH, Chilvers ER, Robbins PA, Percy MJ, Simon MC, Johnson RS, Renshaw SA, Whyte MK, Walmsley SR. Thompson AA, et al. Blood. 2014 Jan 16;123(3):366-76. doi: 10.1182/blood-2013-05-500207. Epub 2013 Nov 6. Blood. 2014. PMID: 24196071 Free PMC article.
MET is required for the recruitment of anti-tumoural neutrophils.
Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson AA, Wauters E, Walmsley S, Prenen H, Granot Z, Casazza A, Mazzone M. Finisguerra V, et al. Nature. 2015 Jun 18;522(7556):349-53. doi: 10.1038/nature14407. Epub 2015 May 18. Nature. 2015. PMID: 25985180 Free PMC article.
Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression.
Jones R, McDonald KE, Willson JA, Ghesquière B, Sammut D, Daniel E, Harris AJ, Lewis A, Thompson AA, Dickinson RS, Plant T, Murphy F, Sadiku P, Keevil BG, Carmeliet P, Whyte MK, Newell-Price J, Walmsley SR. Jones R, et al. Blood. 2016 May 26;127(21):2641-4. doi: 10.1182/blood-2016-02-696922. Epub 2016 Mar 22. Blood. 2016. PMID: 27006389 Free PMC article. No abstract available.
Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis.
Sadiku P, Willson JA, Ryan EM, Sammut D, Coelho P, Watts ER, Grecian R, Young JM, Bewley M, Arienti S, Mirchandani AS, Sanchez Garcia MA, Morrison T, Zhang A, Reyes L, Griessler T, Jheeta P, Paterson GG, Graham CJ, Thomson JP, Baillie K, Thompson AAR, Morgan JM, Acosta-Sanchez A, Dardé VM, Duran J, Guinovart JJ, Rodriguez-Blanco G, Von Kriegsheim A, Meehan RR, Mazzone M, Dockrell DH, Ghesquiere B, Carmeliet P, Whyte MKB, Walmsley SR. Sadiku P, et al. Among authors: thompson aar. Cell Metab. 2021 Feb 2;33(2):411-423.e4. doi: 10.1016/j.cmet.2020.11.016. Epub 2020 Dec 10. Cell Metab. 2021. PMID: 33306983 Free PMC article.
Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis.
Sadiku P, Willson JA, Ryan EM, Sammut D, Coelho P, Watts ER, Grecian R, Young JM, Bewley M, Arienti S, Mirchandani AS, Sanchez Garcia MA, Morrison T, Zhang A, Reyes L, Griessler T, Jheeta P, Paterson GG, Graham CJ, Thomson JP, Baillie K, Thompson AAR, Morgan JM, Acosta-Sanchez A, Dardé VM, Duran J, Guinovart JJ, Rodriguez-Blanco G, Von Kriegsheim A, Meehan RR, Mazzone M, Dockrell DH, Ghesquiere B, Carmeliet P, Whyte MKB, Walmsley SR. Sadiku P, et al. Among authors: thompson aar. Cell Metab. 2021 May 4;33(5):1062-1064. doi: 10.1016/j.cmet.2021.03.018. Cell Metab. 2021. PMID: 33951466 Free PMC article. No abstract available.
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination.
Liew F, Talwar S, Cross A, Willett BJ, Scott S, Logan N, Siggins MK, Swieboda D, Sidhu JK, Efstathiou C, Moore SC, Davis C, Mohamed N, Nunag J, King C, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard L, Wootton DG, Dunachie S, Quint JK, Evans RA, Wain LV, Fontanella S, de Silva TI, Ho A, Harrison E, Baillie JK, Semple MG, Brightling C, Thwaites RS, Turtle L, Openshaw PJM; ISARIC4C Investigators; PHOSP-COVID collaborative group. Liew F, et al. Among authors: thompson aar. EBioMedicine. 2023 Jan;87:104402. doi: 10.1016/j.ebiom.2022.104402. Epub 2022 Dec 19. EBioMedicine. 2023. PMID: 36543718 Free PMC article.
117 results