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Viruses transfer the antiviral second messenger cGAMP between cells.
Bridgeman A, Maelfait J, Davenne T, Partridge T, Peng Y, Mayer A, Dong T, Kaever V, Borrow P, Rehwinkel J. Bridgeman A, et al. Science. 2015 Sep 11;349(6253):1228-32. doi: 10.1126/science.aab3632. Epub 2015 Jul 30. Science. 2015. PMID: 26229117 Free PMC article.
Interferon induction held captive in tumor cells.
Bridgeman A, Rehwinkel J. Bridgeman A, et al. Mol Cell. 2021 Oct 21;81(20):4109-4110. doi: 10.1016/j.molcel.2021.10.004. Mol Cell. 2021. PMID: 34686311 Free article.
Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.
Maelfait J, Liverpool L, Bridgeman A, Ragan KB, Upton JW, Rehwinkel J. Maelfait J, et al. Among authors: bridgeman a. EMBO J. 2017 Sep 1;36(17):2529-2543. doi: 10.15252/embj.201796476. Epub 2017 Jul 17. EMBO J. 2017. PMID: 28716805 Free PMC article.
Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.
Chauveau L, Bridgeman A, Tan TK, Beveridge R, Frost JN, Rijal P, Pedroza-Pacheco I, Partridge T, Gilbert-Jaramillo J, Knight ML, Liu X, Russell RA, Borrow P, Drakesmith H, Townsend AR, Rehwinkel J. Chauveau L, et al. Among authors: bridgeman a. EMBO Rep. 2021 Aug 4;22(8):e52447. doi: 10.15252/embr.202152447. Epub 2021 Jun 18. EMBO Rep. 2021. PMID: 34142428 Free PMC article.
The RNA sensor MDA5 detects SARS-CoV-2 infection.
Sampaio NG, Chauveau L, Hertzog J, Bridgeman A, Fowler G, Moonen JP, Dupont M, Russell RA, Noerenberg M, Rehwinkel J. Sampaio NG, et al. Among authors: bridgeman a. Sci Rep. 2021 Jul 1;11(1):13638. doi: 10.1038/s41598-021-92940-3. Sci Rep. 2021. PMID: 34211037 Free PMC article.
168 results