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Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics.
Wang H, Barbieri CE, He J, Gao Y, Shi T, Wu C, Schepmoes AA, Fillmore TL, Chae SS, Huang D, Mosquera JM, Qian WJ, Smith RD, Srivastava S, Kagan J, Camp DG 2nd, Rodland KD, Rubin MA, Liu T. Wang H, et al. Among authors: huang d. J Transl Med. 2017 Aug 15;15(1):175. doi: 10.1186/s12967-017-1276-7. J Transl Med. 2017. PMID: 28810879 Free PMC article.
SPOP mutation leads to genomic instability in prostate cancer.
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA. Boysen G, et al. Among authors: huang d, huang j. Elife. 2015 Sep 16;4:e09207. doi: 10.7554/eLife.09207. Elife. 2015. PMID: 26374986 Free PMC article.
G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer.
Mukhopadhyay C, Yang C, Xu L, Liu D, Wang Y, Huang D, Deonarine LD, Cyrta J, Davicioni E, Sboner A, Robinson BD, Chinnaiyan AM, Rubin MA, Barbieri CE, Zhou P. Mukhopadhyay C, et al. Among authors: huang d. Nat Commun. 2021 Nov 18;12(1):6662. doi: 10.1038/s41467-021-27024-x. Nat Commun. 2021. PMID: 34795264 Free PMC article.
SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.
Blattner M, Liu D, Robinson BD, Huang D, Poliakov A, Gao D, Nataraj S, Deonarine LD, Augello MA, Sailer V, Ponnala L, Ittmann M, Chinnaiyan AM, Sboner A, Chen Y, Rubin MA, Barbieri CE. Blattner M, et al. Among authors: huang d. Cancer Cell. 2017 Mar 13;31(3):436-451. doi: 10.1016/j.ccell.2017.02.004. Cancer Cell. 2017. PMID: 28292441 Free PMC article.
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.
Grbesa I, Augello MA, Liu D, McNally DR, Gaffney CD, Huang D, Lin K, Ivenitsky D, Goueli R, Robinson BD, Khani F, Deonarine LD, Blattner M, Elemento O, Davicioni E, Sboner A, Barbieri CE. Grbesa I, et al. Among authors: huang d. Cell Rep. 2021 Sep 7;36(10):109625. doi: 10.1016/j.celrep.2021.109625. Cell Rep. 2021. PMID: 34496233 Free PMC article.
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE. Augello MA, et al. Among authors: huang d. Cancer Cell. 2019 Apr 15;35(4):603-617.e8. doi: 10.1016/j.ccell.2019.03.001. Epub 2019 Mar 28. Cancer Cell. 2019. PMID: 30930119 Free PMC article.
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE. Augello MA, et al. Among authors: huang d. Cancer Cell. 2019 May 13;35(5):817-819. doi: 10.1016/j.ccell.2019.04.012. Cancer Cell. 2019. PMID: 31085180 Free article. No abstract available.
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