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Page 1
Novel Treatments for Airway Disease.
Wechsler ME, Akuthota P, Khoury P. Wechsler ME, et al. N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. N Engl J Med. 2017. PMID: 28812971 No abstract available.
Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.
Wechsler ME, Akuthota P, Jayne D, Khoury P, Klion A, Langford CA, Merkel PA, Moosig F, Specks U, Cid MC, Luqmani R, Brown J, Mallett S, Philipson R, Yancey SW, Steinfeld J, Weller PF, Gleich GJ; EGPA Mepolizumab Study Team. Wechsler ME, et al. N Engl J Med. 2017 May 18;376(20):1921-1932. doi: 10.1056/NEJMoa1702079. N Engl J Med. 2017. PMID: 28514601 Free PMC article. Clinical Trial.
Novel Treatments for Airway Disease.
Wechsler ME, Akuthota P, Khoury P. Wechsler ME, et al. N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. N Engl J Med. 2017. PMID: 28792869 No abstract available.
Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).
Khoury P, Akuthota P, Ackerman SJ, Arron JR, Bochner BS, Collins MH, Kahn JE, Fulkerson PC, Gleich GJ, Gopal-Srivastava R, Jacobsen EA, Leiferman KM, Francesca LS, Mathur SK, Minnicozzi M, Prussin C, Rothenberg ME, Roufosse F, Sable K, Simon D, Simon HU, Spencer LA, Steinfeld J, Wardlaw AJ, Wechsler ME, Weller PF, Klion AD. Khoury P, et al. Among authors: wechsler me. J Leukoc Biol. 2018 Jul;104(1):69-83. doi: 10.1002/JLB.5MR0118-028R. Epub 2018 Apr 19. J Leukoc Biol. 2018. PMID: 29672914 Free PMC article. Review.
Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis.
Steinfeld J, Bradford ES, Brown J, Mallett S, Yancey SW, Akuthota P, Cid MC, Gleich GJ, Jayne D, Khoury P, Langford CA, Merkel PA, Moosig F, Specks U, Weller PF, Wechsler ME. Steinfeld J, et al. Among authors: wechsler me. J Allergy Clin Immunol. 2019 Jun;143(6):2170-2177. doi: 10.1016/j.jaci.2018.11.041. Epub 2018 Dec 19. J Allergy Clin Immunol. 2019. PMID: 30578883 Free PMC article. Clinical Trial.
Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features.
Dong ZM, Lin E, Wechsler ME, Weller PF, Klion AD, Bochner BS, Delker DA, Hazel MW, Fairfax K, Khoury P, Akuthota P, Merkel PA, Dyer AM, Langford C, Specks U, Gleich GJ, Chinchilli VM, Raby B, Yandell M, Clayton F. Dong ZM, et al. Among authors: wechsler me. Am J Pathol. 2020 Jul;190(7):1438-1448. doi: 10.1016/j.ajpath.2020.03.005. Epub 2020 Apr 3. Am J Pathol. 2020. PMID: 32251643 Free PMC article.
The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.
Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, Billheimer D, Bleecker ER, Cardet JC, Castro M, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Holguin F, Jain S, Kenyon NJ, Krishnan JA, Kraft M, Kumar R, Liu MC, Ly NP, Moy JN, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Wechsler ME, Wenzel SE, White SR. Ivanova A, et al. Among authors: wechsler me. J Biopharm Stat. 2020 Nov 1;30(6):1026-1037. doi: 10.1080/10543406.2020.1821705. Epub 2020 Sep 17. J Biopharm Stat. 2020. PMID: 32941098 Free PMC article.
PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment.
Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. Israel E, et al. Among authors: wechsler me. J Allergy Clin Immunol. 2021 May;147(5):1594-1601. doi: 10.1016/j.jaci.2021.01.037. Epub 2021 Mar 2. J Allergy Clin Immunol. 2021. PMID: 33667479 Free PMC article.
Defining a Severe Asthma Super-Responder: Findings from a Delphi Process.
Upham JW, Le Lievre C, Jackson DJ, Masoli M, Wechsler ME, Price DB; Delphi Panel. Upham JW, et al. Among authors: wechsler me. J Allergy Clin Immunol Pract. 2021 Nov;9(11):3997-4004. doi: 10.1016/j.jaip.2021.06.041. Epub 2021 Jul 13. J Allergy Clin Immunol Pract. 2021. PMID: 34271216
Introducing the Severe Asthma Series of Invited Reviews.
Akuthota P, Jackson DJ, Wechsler ME. Akuthota P, et al. Among authors: wechsler me. Chest. 2021 Oct;160(4):1151-1152. doi: 10.1016/j.chest.2021.08.056. Chest. 2021. PMID: 34625156 No abstract available.
297 results