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Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Pancera M, Lai YT, Bylund T, Druz A, Narpala S, O'Dell S, Schön A, Bailer RT, Chuang GY, Geng H, Louder MK, Rawi R, Soumana DI, Finzi A, Herschhorn A, Madani N, Sodroski J, Freire E, Langley DR, Mascola JR, McDermott AB, Kwong PD. Pancera M, et al. Among authors: schon a. Nat Chem Biol. 2017 Oct;13(10):1115-1122. doi: 10.1038/nchembio.2460. Epub 2017 Aug 21. Nat Chem Biol. 2017. PMID: 28825711 Free PMC article.
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.
Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB 3rd, Sodroski JG. Si Z, et al. Among authors: schon a. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5036-41. doi: 10.1073/pnas.0307953101. Epub 2004 Mar 29. Proc Natl Acad Sci U S A. 2004. PMID: 15051887 Free PMC article.
Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.
Pancera M, Lebowitz J, Schön A, Zhu P, Freire E, Kwong PD, Roux KH, Sodroski J, Wyatt R. Pancera M, et al. Among authors: schon a. J Virol. 2005 Aug;79(15):9954-69. doi: 10.1128/JVI.79.15.9954-9969.2005. J Virol. 2005. PMID: 16014956 Free PMC article.
177 results