Parnell TJ - Search Results

1

A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.

Sdano MA, Fulcher JM, Palani S, Chandrasekharan MB, Parnell TJ, Whitby FG, Formosa T, Hill CP. Sdano MA, et al. Among authors: parnell tj. Elife. 2017 Aug 16;6:e28723. doi: 10.7554/eLife.28723. Elife. 2017. PMID: 28826505 Free PMC article.

2

The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism.

Parnell TJ, Schlichter A, Wilson BG, Cairns BR. Parnell TJ, et al. Elife. 2015 Mar 30;4:e06073. doi: 10.7554/eLife.06073. Elife. 2015. PMID: 25821983 Free PMC article.

3

Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.

Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB. Huang F, et al. Among authors: parnell tj. J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085. Epub 2015 Oct 8. J Biol Chem. 2015. PMID: 26451043 Free PMC article.

4

Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription.

Ramakrishnan S, Pokhrel S, Palani S, Pflueger C, Parnell TJ, Cairns BR, Bhaskara S, Chandrasekharan MB. Ramakrishnan S, et al. Among authors: parnell tj. Nat Commun. 2016 Jun 21;7:11949. doi: 10.1038/ncomms11949. Nat Commun. 2016. PMID: 27325136 Free PMC article.

5

Establishment and Maintenance of Chromatin Architecture Are Promoted Independently of Transcription by the Histone Chaperone FACT and H3-K56 Acetylation in Saccharomyces cerevisiae.

McCullough LL, Pham TH, Parnell TJ, Connell Z, Chandrasekharan MB, Stillman DJ, Formosa T. McCullough LL, et al. Among authors: parnell tj. Genetics. 2019 Mar;211(3):877-892. doi: 10.1534/genetics.118.301853. Epub 2019 Jan 24. Genetics. 2019. PMID: 30679261 Free PMC article.

6

Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes.

Schlichter A, Kasten MM, Parnell TJ, Cairns BR. Schlichter A, et al. Among authors: parnell tj. Elife. 2020 Jun 4;9:e58130. doi: 10.7554/eLife.58130. Elife. 2020. PMID: 32496195 Free PMC article.

7

The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II.

Connell Z, Parnell TJ, McCullough LL, Hill CP, Formosa T. Connell Z, et al. Among authors: parnell tj. Nucleic Acids Res. 2022 Jan 25;50(2):784-802. doi: 10.1093/nar/gkab1262. Nucleic Acids Res. 2022. PMID: 34967414 Free PMC article.

8

Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.

Shukla PK, Bissell JE, Kumar S, Pokhrel S, Palani S, Radmall KS, Obidi O, Parnell TJ, Brasch J, Shrieve DC, Chandrasekharan MB. Shukla PK, et al. Among authors: parnell tj. Nucleic Acids Res. 2023 Mar 21;51(5):2117-2136. doi: 10.1093/nar/gkad012. Nucleic Acids Res. 2023. PMID: 36715322 Free PMC article.

9

RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes.

Parnell TJ, Huff JT, Cairns BR. Parnell TJ, et al. EMBO J. 2008 Jan 9;27(1):100-10. doi: 10.1038/sj.emboj.7601946. Epub 2007 Dec 6. EMBO J. 2008. PMID: 18059476 Free PMC article.

10

Cancer-Associated Gain-of-Function Mutations Activate a SWI/SNF-Family Regulatory Hub.

Clapier CR, Verma N, Parnell TJ, Cairns BR. Clapier CR, et al. Among authors: parnell tj. Mol Cell. 2020 Nov 19;80(4):712-725.e5. doi: 10.1016/j.molcel.2020.09.024. Epub 2020 Oct 14. Mol Cell. 2020. PMID: 33058778 Free PMC article.

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