Tatsis EC - Search Results

1

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate.

Tatsis EC, Carqueijeiro I, Dugé de Bernonville T, Franke J, Dang TT, Oudin A, Lanoue A, Lafontaine F, Stavrinides AK, Clastre M, Courdavault V, O'Connor SE. Tatsis EC, et al. Nat Commun. 2017 Aug 22;8(1):316. doi: 10.1038/s41467-017-00154-x. Nat Commun. 2017. PMID: 28827772 Free PMC article.

2

Unlocking the diversity of alkaloids in Catharanthus roseus: nuclear localization suggests metabolic channeling in secondary metabolism.

Stavrinides A, Tatsis EC, Foureau E, Caputi L, Kellner F, Courdavault V, O'Connor SE. Stavrinides A, et al. Among authors: tatsis ec. Chem Biol. 2015 Mar 19;22(3):336-41. doi: 10.1016/j.chembiol.2015.02.006. Epub 2015 Mar 12. Chem Biol. 2015. PMID: 25772467 Free PMC article.

3

New developments in engineering plant metabolic pathways.

Tatsis EC, O'Connor SE. Tatsis EC, et al. Curr Opin Biotechnol. 2016 Dec;42:126-132. doi: 10.1016/j.copbio.2016.04.012. Epub 2016 Apr 29. Curr Opin Biotechnol. 2016. PMID: 27132124 Free article. Review.

4

Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity.

Stavrinides A, Tatsis EC, Caputi L, Foureau E, Stevenson CE, Lawson DM, Courdavault V, O'Connor SE. Stavrinides A, et al. Among authors: tatsis ec. Nat Commun. 2016 Jul 15;7:12116. doi: 10.1038/ncomms12116. Nat Commun. 2016. PMID: 27418042 Free PMC article.

5

An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole.

Payne RM, Xu D, Foureau E, Teto Carqueijeiro MI, Oudin A, Bernonville TD, Novak V, Burow M, Olsen CE, Jones DM, Tatsis EC, Pendle A, Ann Halkier B, Geu-Flores F, Courdavault V, Nour-Eldin HH, O'Connor SE. Payne RM, et al. Among authors: tatsis ec. Nat Plants. 2017 Jan 13;3:16208. doi: 10.1038/nplants.2016.208. Nat Plants. 2017. PMID: 28085153 Free PMC article.

6

Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina.

Dang TT, Franke J, Tatsis E, O'Connor SE. Dang TT, et al. Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9440-9444. doi: 10.1002/anie.201705010. Epub 2017 Jul 12. Angew Chem Int Ed Engl. 2017. PMID: 28654178 Free PMC article.

7

Discovery of a Short-Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid.

Stavrinides AK, Tatsis EC, Dang TT, Caputi L, Stevenson CEM, Lawson DM, Schneider B, O'Connor SE. Stavrinides AK, et al. Among authors: tatsis ec. Chembiochem. 2018 May 4;19(9):940-948. doi: 10.1002/cbic.201700621. Epub 2018 Mar 22. Chembiochem. 2018. PMID: 29424954 Free PMC article.

8

Gene Discovery in Gelsemium Highlights Conserved Gene Clusters in Monoterpene Indole Alkaloid Biosynthesis.

Franke J, Kim J, Hamilton JP, Zhao D, Pham GM, Wiegert-Rininger K, Crisovan E, Newton L, Vaillancourt B, Tatsis E, Buell CR, O'Connor SE. Franke J, et al. Chembiochem. 2019 Jan 2;20(1):83-87. doi: 10.1002/cbic.201800592. Epub 2018 Nov 13. Chembiochem. 2019. PMID: 30300974

9

Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism.

Langley C, Tatsis E, Hong B, Nakamura Y, Paetz C, Stevenson CEM, Basquin J, Lawson DM, Caputi L, O'Connor SE. Langley C, et al. Angew Chem Int Ed Engl. 2022 Nov 25;61(48):e202210934. doi: 10.1002/anie.202210934. Epub 2022 Oct 26. Angew Chem Int Ed Engl. 2022. PMID: 36198083 Free PMC article.

10

A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology.

Casini A, Chang FY, Eluere R, King AM, Young EM, Dudley QM, Karim A, Pratt K, Bristol C, Forget A, Ghodasara A, Warden-Rothman R, Gan R, Cristofaro A, Borujeni AE, Ryu MH, Li J, Kwon YC, Wang H, Tatsis E, Rodriguez-Lopez C, O'Connor S, Medema MH, Fischbach MA, Jewett MC, Voigt C, Gordon DB. Casini A, et al. J Am Chem Soc. 2018 Mar 28;140(12):4302-4316. doi: 10.1021/jacs.7b13292. Epub 2018 Mar 16. J Am Chem Soc. 2018. PMID: 29480720

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