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Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
Huang M, Modeste E, Dammer E, Merino P, Taylor G, Duong DM, Deng Q, Holler CJ, Gearing M, Dickson D, Seyfried NT, Kukar T. Huang M, et al. Among authors: holler cj. Acta Neuropathol Commun. 2020 Oct 7;8(1):163. doi: 10.1186/s40478-020-01037-x. Acta Neuropathol Commun. 2020. PMID: 33028409 Free PMC article.
Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
McEachin ZT, Gendron TF, Raj N, García-Murias M, Banerjee A, Purcell RH, Ward PJ, Todd TW, Merritt-Garza ME, Jansen-West K, Hales CM, García-Sobrino T, Quintáns B, Holler CJ, Taylor G, San Millán B, Teijeira S, Yamashita T, Ohkubo R, Boulis NM, Xu C, Wen Z, Streichenberger N; Neuro–CEB Neuropathology Network; Fogel BL, Kukar T, Abe K, Dickson DW, Arias M, Glass JD, Jiang J, Tansey MG, Sobrido MJ, Petrucelli L, Rossoll W, Bassell GJ. McEachin ZT, et al. Among authors: holler cj. Neuron. 2020 Jul 22;107(2):292-305.e6. doi: 10.1016/j.neuron.2020.04.011. Epub 2020 May 5. Neuron. 2020. PMID: 32375063 Free PMC article.
BACE1 and BACE2 enzymatic activities in Alzheimer's disease.
Ahmed RR, Holler CJ, Webb RL, Li F, Beckett TL, Murphy MP. Ahmed RR, et al. Among authors: holler cj. J Neurochem. 2010 Feb;112(4):1045-53. doi: 10.1111/j.1471-4159.2009.06528.x. Epub 2009 Dec 4. J Neurochem. 2010. PMID: 19968762 Free PMC article.
BACE2 expression increases in human neurodegenerative disease.
Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. Holler CJ, et al. Am J Pathol. 2012 Jan;180(1):337-50. doi: 10.1016/j.ajpath.2011.09.034. Epub 2011 Nov 7. Am J Pathol. 2012. PMID: 22074738 Free PMC article.
16 results