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Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors.
Kickinger S, Al-Khawaja A, Haugaard AS, Lie MEK, Bavo F, Löffler R, Damgaard M, Ecker GF, Frølund B, Wellendorph P. Kickinger S, et al. Among authors: lie mek. Sci Rep. 2020 Aug 3;10(1):12992. doi: 10.1038/s41598-020-69908-w. Sci Rep. 2020. PMID: 32747622 Free PMC article.
Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1.
Kickinger S, Lie MEK, Suemasa A, Al-Khawaja A, Fujiwara K, Watanabe M, Wilhelmsen KS, Falk-Petersen CB, Frølund B, Shuto S, Ecker GF, Wellendorph P. Kickinger S, et al. Among authors: lie mek. Front Chem. 2021 Sep 14;9:736457. doi: 10.3389/fchem.2021.736457. eCollection 2021. Front Chem. 2021. PMID: 34595152 Free PMC article.
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