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The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.
Mathews II, Allison K, Robbins T, Lyubimov AY, Uervirojnangkoorn M, Brunger AT, Khosla C, DeMirci H, McPhillips SE, Hollenbeck M, Soltis M, Cohen AE. Mathews II, et al. Biochemistry. 2017 Sep 12;56(36):4751-4756. doi: 10.1021/acs.biochem.7b00711. Epub 2017 Aug 31. Biochemistry. 2017. PMID: 28832129 Free PMC article.
Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2.
Sanders B, Pokhrel S, Labbe A, Mathews I, Cooper C, Davidson R, Phillips G, Weiss K, Zhang Q, O'Neill H, Kaur M, Ferrins L, Schmidt J, Reichard W, Surendranathan S, Parvathareddy J, Phillips L, Rainville C, Sterner D, Kumaran D, Andi B, Babnigg G, Moriarrty N, Adams P, Joachimiak A, Hurst B, Kumar S, Butt T, Jonsson C, Wakatsuki S, Galanie S, Head M, Parks J. Sanders B, et al. Res Sq [Preprint]. 2022 Jul 21:rs.3.rs-906621. doi: 10.21203/rs.3.rs-906621/v1. Res Sq. 2022. Update in: Nat Commun. 2023 Mar 28;14(1):1733. doi: 10.1038/s41467-023-37254-w PMID: 34642689 Free PMC article. Updated. Preprint.
New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection.
Soltis SM, Cohen AE, Deacon A, Eriksson T, González A, McPhillips S, Chui H, Dunten P, Hollenbeck M, Mathews I, Miller M, Moorhead P, Phizackerley RP, Smith C, Song J, van dem Bedem H, Ellis P, Kuhn P, McPhillips T, Sauter N, Sharp K, Tsyba I, Wolf G. Soltis SM, et al. Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1210-21. doi: 10.1107/S0907444908030564. Epub 2008 Nov 18. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 19018097 Free PMC article.
Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.
Stevenson HP, Makhov AM, Calero M, Edwards AL, Zeldin OB, Mathews II, Lin G, Barnes CO, Santamaria H, Ross TM, Soltis SM, Khosla C, Nagarajan V, Conway JF, Cohen AE, Calero G. Stevenson HP, et al. Among authors: mathews ii. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8470-5. doi: 10.1073/pnas.1400240111. Epub 2014 May 28. Proc Natl Acad Sci U S A. 2014. PMID: 24872454 Free PMC article.
76 results